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High resolution structural evidence suggests the Sarcoplasmic Reticulum forms microdomains with Acidic Stores (lysosomes) in the heart

Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP) stimulates calcium release from acidic stores such as lysosomes and is a highly potent calcium-mobilising second messenger. NAADP plays an important role in calcium signalling in the heart under basal conditions and following β-adrenergic stress....

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Detalles Bibliográficos
Autores principales: Aston, Daniel, Capel, Rebecca A., Ford, Kerrie L., Christian, Helen C., Mirams, Gary R., Rog-Zielinska, Eva A., Kohl, Peter, Galione, Antony, Burton, Rebecca A. B., Terrar, Derek A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5240626/
https://www.ncbi.nlm.nih.gov/pubmed/28094777
http://dx.doi.org/10.1038/srep40620

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