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High resolution structural evidence suggests the Sarcoplasmic Reticulum forms microdomains with Acidic Stores (lysosomes) in the heart
Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP) stimulates calcium release from acidic stores such as lysosomes and is a highly potent calcium-mobilising second messenger. NAADP plays an important role in calcium signalling in the heart under basal conditions and following β-adrenergic stress....
Autores principales: | Aston, Daniel, Capel, Rebecca A., Ford, Kerrie L., Christian, Helen C., Mirams, Gary R., Rog-Zielinska, Eva A., Kohl, Peter, Galione, Antony, Burton, Rebecca A. B., Terrar, Derek A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5240626/ https://www.ncbi.nlm.nih.gov/pubmed/28094777 http://dx.doi.org/10.1038/srep40620 |
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