Systematic Identification of Oncogenic EGFR Interaction Partners

The epidermal growth factor receptor (EGFR) is a receptor tyrosine kinase (TK) that—once activated upon ligand binding—leads to receptor dimerization, recruitment of protein complexes, and activation of multiple signaling cascades. The EGFR is frequently overexpressed or mutated in various cancers l...

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Detalles Bibliográficos
Autores principales: Petschnigg, Julia, Kotlyar, Max, Blair, Louise, Jurisica, Igor, Stagljar, Igor, Ketteler, Robin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5240790/
https://www.ncbi.nlm.nih.gov/pubmed/27956147
http://dx.doi.org/10.1016/j.jmb.2016.12.006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5240790/
https://www.ncbi.nlm.nih.gov/pubmed/27956147
http://dx.doi.org/10.1016/j.jmb.2016.12.006

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