Small molecule absorption by PDMS in the context of drug response bioassays

The polymer polydimethylsiloxane (PDMS) is widely used to build microfluidic devices compatible with cell culture. Whilst convenient in manufacture, PDMS has the disadvantage that it can absorb small molecules such as drugs. In microfluidic devices like “Organs-on-Chip”, designed to examine cell beh...

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Detalles Bibliográficos
Autores principales: van Meer, B.J., de Vries, H., Firth, K.S.A., van Weerd, J., Tertoolen, L.G.J., Karperien, H.B.J., Jonkheijm, P., Denning, C., IJzerman, A.P., Mummery, C.L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5240851/
https://www.ncbi.nlm.nih.gov/pubmed/27856254
http://dx.doi.org/10.1016/j.bbrc.2016.11.062

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