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Endogenous Semaphorin-7A Impedes Human Lung Fibroblast Differentiation

Semaphorin-7A is a glycosylphosphatidylinositol-anchored protein, initially characterized as an axon guidance protein. Semaphorin-7A also contributes to immune cell regulation and may be an essential pro-fibrotic factor when expressed by non-fibroblast cell types (exogenous). In mouse models, semaph...

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Detalles Bibliográficos
Autores principales: Esnault, Stephane, Torr, Elizabeth E., Bernau, Ksenija, Johansson, Mats W., Kelly, Elizabeth A., Sandbo, Nathan, Jarjour, Nizar N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5240965/
https://www.ncbi.nlm.nih.gov/pubmed/28095470
http://dx.doi.org/10.1371/journal.pone.0170207

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