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Non-Homologous End Joining and Homology Directed DNA Repair Frequency of Double-Stranded Breaks Introduced by Genome Editing Reagents

Genome editing using transcription-activator like effector nucleases or RNA guided nucleases allows one to precisely engineer desired changes within a given target sequence. The genome editing reagents introduce double stranded breaks (DSBs) at the target site which can then undergo DNA repair by no...

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Detalles Bibliográficos
Autores principales:	Zaboikin, Michail, Zaboikina, Tatiana, Freter, Carl, Srinivasakumar, Narasimhachar
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5241150/ https://www.ncbi.nlm.nih.gov/pubmed/28095454 http://dx.doi.org/10.1371/journal.pone.0169931

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