Genetics and genomics etiology of nonsyndromic orofacial clefts

Orofacial clefts (OFC) are complex birth defects. Studies using contemporary genomic techniques, bioinformatics, and statistical analyses have led to appreciable advances in identifying the causes of syndromic forms of clefts. This commentary gives an overview of the important cleft gene discoveries...

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Detalles Bibliográficos
Autores principales: Adeyemo, Wasiu L., Butali, Azeez
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Invited Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5241211/
https://www.ncbi.nlm.nih.gov/pubmed/28116324
http://dx.doi.org/10.1002/mgg3.272
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author Adeyemo, Wasiu L.
Butali, Azeez
author_facet Adeyemo, Wasiu L.
Butali, Azeez
author_sort Adeyemo, Wasiu L.
collection PubMed
description Orofacial clefts (OFC) are complex birth defects. Studies using contemporary genomic techniques, bioinformatics, and statistical analyses have led to appreciable advances in identifying the causes of syndromic forms of clefts. This commentary gives an overview of the important cleft gene discoveries found using various genomic methods and tools. [Image: see text]
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spelling pubmed-52412112017-01-23 Genetics and genomics etiology of nonsyndromic orofacial clefts Adeyemo, Wasiu L. Butali, Azeez Mol Genet Genomic Med Invited Commentary Orofacial clefts (OFC) are complex birth defects. Studies using contemporary genomic techniques, bioinformatics, and statistical analyses have led to appreciable advances in identifying the causes of syndromic forms of clefts. This commentary gives an overview of the important cleft gene discoveries found using various genomic methods and tools. [Image: see text] John Wiley and Sons Inc. 2017-01-17 /pmc/articles/PMC5241211/ /pubmed/28116324 http://dx.doi.org/10.1002/mgg3.272 Text en © 2017 The Authors. Molecular Genetics & Genomic Medicine published by Wiley Periodicals, Inc. This is an open access article under the terms of the Creative Commons Attribution (http://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Invited Commentary
Adeyemo, Wasiu L.
Butali, Azeez
Genetics and genomics etiology of nonsyndromic orofacial clefts
title Genetics and genomics etiology of nonsyndromic orofacial clefts
title_full Genetics and genomics etiology of nonsyndromic orofacial clefts
title_fullStr Genetics and genomics etiology of nonsyndromic orofacial clefts
title_full_unstemmed Genetics and genomics etiology of nonsyndromic orofacial clefts
title_short Genetics and genomics etiology of nonsyndromic orofacial clefts
title_sort genetics and genomics etiology of nonsyndromic orofacial clefts
topic Invited Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5241211/
https://www.ncbi.nlm.nih.gov/pubmed/28116324
http://dx.doi.org/10.1002/mgg3.272
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