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Priming increases the anti-tumor effect and therapeutic window of (177)Lu-octreotate in nude mice bearing human small intestine neuroendocrine tumor GOT1
BACKGROUND: (177)Lu-[DOTA(0), Tyr(3)]-octreotate ((177)Lu-octreotate) is used for treatment of patients with somatostatin receptor (SSTR) expressing neuroendocrine tumors. However, complete tumor remission is rarely seen, and optimization of treatment protocols is needed. In vitro studies have shown...
Autores principales: | Dalmo, Johanna, Spetz, Johan, Montelius, Mikael, Langen, Britta, Arvidsson, Yvonne, Johansson, Henrik, Parris, Toshima Z., Helou, Khalil, Wängberg, Bo, Nilsson, Ola, Ljungberg, Maria, Forssell-Aronsson, Eva |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5241264/ https://www.ncbi.nlm.nih.gov/pubmed/28097640 http://dx.doi.org/10.1186/s13550-016-0247-y |
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