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Neurotoxicity in Preclinical Models of Occupational Exposure to Organophosphorus Compounds

Organophosphorus (OPs) compounds are widely used as insecticides, plasticizers, and fuel additives. These compounds potently inhibit acetylcholinesterase (AChE), the enzyme that inactivates acetylcholine at neuronal synapses, and acute exposure to high OP levels can cause cholinergic crisis in human...

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Detalles Bibliográficos
Autores principales: Voorhees, Jaymie R., Rohlman, Diane S., Lein, Pamela J., Pieper, Andrew A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5241311/
https://www.ncbi.nlm.nih.gov/pubmed/28149268
http://dx.doi.org/10.3389/fnins.2016.00590

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