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Neurotoxicity in Preclinical Models of Occupational Exposure to Organophosphorus Compounds
Organophosphorus (OPs) compounds are widely used as insecticides, plasticizers, and fuel additives. These compounds potently inhibit acetylcholinesterase (AChE), the enzyme that inactivates acetylcholine at neuronal synapses, and acute exposure to high OP levels can cause cholinergic crisis in human...
Autores principales: | Voorhees, Jaymie R., Rohlman, Diane S., Lein, Pamela J., Pieper, Andrew A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5241311/ https://www.ncbi.nlm.nih.gov/pubmed/28149268 http://dx.doi.org/10.3389/fnins.2016.00590 |
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