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Novel therapeutic approaches targeting L-type amino acid transporters for cancer treatment

L-type amino acid transporters (LATs) mainly assist the uptake of neutral amino acids into cells. Four LATs (LAT1, LAT2, LAT3 and LAT4) have so far been identified. LAT1 (SLC7A5) has been attracting much attention in the field of cancer research since it is commonly up-regulated in various cancers....

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Detalles Bibliográficos
Autores principales: Hayashi, Keitaro, Anzai, Naohiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5241523/
https://www.ncbi.nlm.nih.gov/pubmed/28144396
http://dx.doi.org/10.4251/wjgo.v9.i1.21

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