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Continuous cell supply from Krt7-expressing hematopoietic stem cells during native hematopoiesis revealed by targeted in vivo gene transfer method

The nature of hematopoietic stem cells under normal hematopoiesis remained largely unknown due to the limited assays available to monitor their behavior in situ. Here, we develop a new mouse model to transfer genes specifically into the primitive hematopoietic stem cell compartment through the utili...

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Detalles Bibliográficos
Autores principales: Tajima, Yoko, Ito, Keiichi, Umino, Ayumi, Wilkinson, Adam C., Nakauchi, Hiromitsu, Yamazaki, Satoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5241640/
https://www.ncbi.nlm.nih.gov/pubmed/28098173
http://dx.doi.org/10.1038/srep40684

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