Cargando…

Non-pathogenic tissue-resident CD8(+) T cells uniquely accumulate in the brains of lupus-prone mice

Severe lupus often includes psychiatric and neurological sequelae, although the cellular contributors to CNS disease remain poorly defined. Using intravascular staining to discriminate tissue-localized from blood-borne cells, we find substantial accumulation of CD8(+) T cells relative to other lymph...

Descripción completa

Detalles Bibliográficos
Autores principales: Morawski, Peter A., Qi, Chen-Feng, Bolland, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5241651/
https://www.ncbi.nlm.nih.gov/pubmed/28098193
http://dx.doi.org/10.1038/srep40838