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Non-pathogenic tissue-resident CD8(+) T cells uniquely accumulate in the brains of lupus-prone mice
Severe lupus often includes psychiatric and neurological sequelae, although the cellular contributors to CNS disease remain poorly defined. Using intravascular staining to discriminate tissue-localized from blood-borne cells, we find substantial accumulation of CD8(+) T cells relative to other lymph...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5241651/ https://www.ncbi.nlm.nih.gov/pubmed/28098193 http://dx.doi.org/10.1038/srep40838 |