Cargando…

IFN-γ regulates human dental pulp stem cells behavior via NF-κB and MAPK signaling

During caries, dental pulp expresses a range of pro-inflammatory cytokines in response to the infectious challenge. Interferon gamma (IFN-γ) is a dimerized soluble cytokine, which is critical for immune responses. Previous study has demonstrated that IFN-γ at relative high concentration (100 ng/mL)...

Descripción completa

Detalles Bibliográficos
Autores principales:	He, Xinyao, Jiang, Wenkai, Luo, Zhirong, Qu, Tiejun, Wang, Zhihua, Liu, Ningning, Zhang, Yaqing, Cooper, Paul R., He, Wenxi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5241669/ https://www.ncbi.nlm.nih.gov/pubmed/28098169 http://dx.doi.org/10.1038/srep40681

Ejemplares similares

Wheel-Running Exercise Protects Ovariectomized Mice from Bone Loss via IFN-γ-Mediated Suppression of the NF-κB and MAPK Pathways
por: Shen, Hao, et al.
Publicado: (2022)

Transforming growth factor-β1 promotes early odontoblastic differentiation of dental pulp stem cells via activating AKT, Erk1/2 and p38 MAPK pathways
por: Bai, Yu, et al.
Publicado: (2023)

MicroRNA‐22 suppresses NLRP3/CASP1 inflammasome pathway‐mediated proinflammatory cytokine production by targeting the HIF‐1α and NLRP3 in human dental pulp fibroblasts
por: Jiang, Wenkai, et al.
Publicado: (2022)

Stage-Dependent Regulation of Dental Pulp Stem Cell Odontogenic Differentiation by Transforming Growth Factor-β1
por: Bai, Yu, et al.
Publicado: (2022)

IFN-γ Regulates the Expression of MICA in Human Corneal Epithelium Through miRNA4448 and NFκB
por: Wu, Dan, et al.
Publicado: (2018)

Amphiregulin regulates odontogenic differentiation of dental pulp stem cells by activation of mitogen-activated protein kinase and the phosphatidylinositol 3-kinase signaling pathways
por: Li, Junqing, et al.
Publicado: (2022)

NBCe1 Regulates Odontogenic Differentiation of Human Dental Pulp Stem Cells via NF-κB
por: Li, Qin, et al.
Publicado: (2022)

Elevated serum IFN-γand IFN-γ/IL-6 ratio in Kikuchi-Fujimoto disease
por: He, Tingyan, et al.
Publicado: (2023)

Puerarin alleviates osteoporosis in the ovariectomy-induced mice by suppressing osteoclastogenesis via inhibition of TRAF6/ROS-dependent MAPK/NF-κB signaling pathways
por: Xiao, Long, et al.
Publicado: (2020)

Chlorogenic acid rich in coffee pulp extract suppresses inflammatory status by inhibiting the p38, MAPK, and NF-κB pathways
por: Ontawong, Atcharaporn, et al.
Publicado: (2023)

Activation of the NLRP3/caspase-1 inflammasome in human dental pulp tissue and human dental pulp fibroblasts
por: Jiang, Wenkai, et al.
Publicado: (2015)

Exposure to receptor-activator of NFκB ligand renders pre-osteoclasts resistant to IFN-γ by inducing terminal differentiation
por: Huang, Willis, et al.
Publicado: (2003)

LIGHT/IFN‐γ triggers β cells apoptosis via NF‐κB/Bcl2‐dependent mitochondrial pathway
por: Zheng, Quan‐You, et al.
Publicado: (2016)

PPAR γ/Nnat/NF-κB Axis Involved in Promoting Effects of Adiponectin on Preadipocyte Differentiation
por: Yang, Wenkai, et al.
Publicado: (2019)

IFN-τ Displays Anti-Inflammatory Effects on Staphylococcus aureus Endometritis via Inhibiting the Activation of the NF-κB and MAPK Pathways in Mice
por: Zhang, Zhenbiao, et al.
Publicado: (2017)

Biologically Synthesized Rosa rugosa-Based Gold Nanoparticles Suppress Skin Inflammatory Responses via MAPK and NF-κB Signaling Pathway in TNF-α/IFN-γ-Induced HaCaT Keratinocytes
por: Wang, Rongbo, et al.
Publicado: (2022)

Genkwadaphnin Induces IFN-γ via PKD1/NF-κB/STAT1 Dependent Pathway in NK-92 Cells
por: Kang, Ho-Bum, et al.
Publicado: (2014)

The correlation between vitamin D and levels of IFN-γ, NF-κB, thyroid antibodies in down syndrome: study in Indonesian children
por: Hisbiyah, Yuni, et al.
Publicado: (2022)

Dental pulp stem cell-derived exosomes suppress M1 macrophage polarization through the ROS-MAPK-NFκB P65 signaling pathway after spinal cord injury
por: Liu, Chao, et al.
Publicado: (2022)

Wnt4 prevents apoptosis and inflammation of dental pulp cells induced by LPS by inhibiting the IKK/NF‑κB pathway
por: Ni, Chengli, et al.
Publicado: (2022)

IFN-γ Induces Gastric Cancer Cell Proliferation and Metastasis Through Upregulation of Integrin β3-Mediated NF-κB Signaling
por: Xu, Yuan-Hua, et al.
Publicado: (2018)

STAT3 promotes IFNγ/TNFα‐induced muscle wasting in an NF‐κB‐dependent and IL‐6‐independent manner
por: Ma, Jennifer F, et al.
Publicado: (2017)

Adiporedoxin suppresses endothelial activation via inhibiting MAPK and NF-κB signaling
por: He, Hui, et al.
Publicado: (2016)

Fucosterol Isolated from Dietary Brown Alga Sargassum horneri Protects TNF-α/IFN-γ-Stimulated Human Dermal Fibroblasts Via Regulating Nrf2/HO-1 and NF-κB/MAPK Pathways
por: Kirindage, Kirinde Gedara Isuru Sandanuwan, et al.
Publicado: (2022)

Decreasing NF-κB Expression Enhances Odontoblastic Differentiation and Collagen Expression in Dental Pulp Stem Cells Exposed to Inflammatory Cytokines
por: Hozhabri, Neda S. T., et al.
Publicado: (2015)

The Dental Pulp
por: Sudduth, W. Xavier
Publicado: (1891)

The Dental Pulp
por: Sudduth, W. Xavier
Publicado: (1891)

The Dental Pulp
por: Cravens, Junius E.
Publicado: (1888)

The Dental Pulps
por: Pease, Wm. A.
Publicado: (1878)

Regulation of Human Natural Killer Cell IFN-γ Production by MicroRNA-146a via Targeting the NF-κB Signaling Pathway
por: Wang, Hongwei, et al.
Publicado: (2018)

Recombinant Klotho attenuates IFNγ receptor signaling and SAMHD1 expression through blocking NF-κB translocation in glomerular mesangial cells
por: Tsai, Kuen-Daw, et al.
Publicado: (2023)

Dental Pulp Stem Cell Mechanoresponsiveness: Effects of Mechanical Stimuli on Dental Pulp Stem Cell Behavior
por: Marrelli, Massimo, et al.
Publicado: (2018)

A Novel Role for IκBζ in the Regulation of IFNγ Production
por: Raices, Raquel M., et al.
Publicado: (2009)

TXNIP/TRX/NF-κB and MAPK/NF-κB pathways involved in the cardiotoxicity induced by Venenum Bufonis in rats
por: Bi, Qi-rui, et al.
Publicado: (2016)

Dental Pulp Defence and Repair Mechanisms in Dental Caries
por: Farges, Jean-Christophe, et al.
Publicado: (2015)

IFN-γ mediates graft-versus-breast cancer effects via enhancing cytotoxic T lymphocyte activity
por: ZHAO, QIANJIE, et al.
Publicado: (2014)

Correction: Decreasing NF-κB Expression Enhances Odontoblastic Differentiation and Collagen Expression in Dental Pulp Stem Cells Exposed to Inflammatory Cytokines
por: Hozhabri, Neda S. T., et al.
Publicado: (2015)

Pannexin3 inhibits TNF‐α‐induced inflammatory response by suppressing NF‐κB signalling pathway in human dental pulp cells
por: Song, Fangfang, et al.
Publicado: (2016)

Paeoniflorin Ameliorates Hyperprolactinemia-Induced Inhibition of Osteoblastogenesis by Suppressing the NF-κB Signaling Pathway
por: Sun, Xiaohong, et al.
Publicado: (2022)

Subanesthetic isoflurane abates ROS-activated MAPK/NF-κB signaling to repress ischemia-induced microglia inflammation and brain injury
por: Yao, Zhiqiang, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_i1cbq58ovotr8aadlsv3gvafor