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Glyco-engineering for the production of recombinant IgA1 with distinct mucin-type O-glycans in plants
IgA nephropathy (IgAN) is a common autoimmune disease that is characterized by formation and deposition of IgA1-containing immune complexes frequently leading to end-stage kidney disease. The IgA1 in these immune complexes carries aberrantly glycosylated O-glycans. In circulating IgA1 these galactos...
Autores principales: | Dicker, Martina, Maresch, Daniel, Strasser, Richard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5241791/ https://www.ncbi.nlm.nih.gov/pubmed/27333379 http://dx.doi.org/10.1080/21655979.2016.1201251 |
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