The clinically approved antiviral drug sofosbuvir inhibits Zika virus replication

Zika virus (ZIKV) is a member of the Flaviviridae family, along with other agents of clinical significance such as dengue (DENV) and hepatitis C (HCV) viruses. Since ZIKV causes neurological disorders during fetal development and in adulthood, antiviral drugs are necessary. Sofosbuvir is clinically...

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Detalles Bibliográficos
Autores principales: Sacramento, Carolina Q., de Melo, Gabrielle R., de Freitas, Caroline S., Rocha, Natasha, Hoelz, Lucas Villas Bôas, Miranda, Milene, Fintelman-Rodrigues, Natalia, Marttorelli, Andressa, Ferreira, André C., Barbosa-Lima, Giselle, Abrantes, Juliana L., Vieira, Yasmine Rangel, Bastos, Mônica M., de Mello Volotão, Eduardo, Nunes, Estevão Portela, Tschoeke, Diogo A., Leomil, Luciana, Loiola, Erick Correia, Trindade, Pablo, Rehen, Stevens K., Bozza, Fernando A., Bozza, Patrícia T., Boechat, Nubia, Thompson, Fabiano L., de Filippis, Ana M. B., Brüning, Karin, Souza, Thiago Moreno L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5241873/
https://www.ncbi.nlm.nih.gov/pubmed/28098253
http://dx.doi.org/10.1038/srep40920

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