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Methods to find out the expression of activated genes
This review deals with the methods of identifying genes that have been activated by inner or outer impulses. The activation and subsequent expression of a gene can be detected by its transcription into a corresponding messenger ribonucleic acid (mRNA). Principles of the methods for identification of...
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| Formato: | Texto |
| Lenguaje: | English |
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BioMed Central
2004
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC524190/ https://www.ncbi.nlm.nih.gov/pubmed/15385048 http://dx.doi.org/10.1186/1477-7827-2-68 |
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| author | Cekan, Sten Z |
| author_facet | Cekan, Sten Z |
| author_sort | Cekan, Sten Z |
| collection | PubMed |
| description | This review deals with the methods of identifying genes that have been activated by inner or outer impulses. The activation and subsequent expression of a gene can be detected by its transcription into a corresponding messenger ribonucleic acid (mRNA). Principles of the methods for identification of individual activated genes, as well as groups of activated genes are described, the former methods being mostly based on subtractive hybridization and serial analysis of gene expression (SAGE), the latter on microarrays. Examples of gene activation by the hormone 17beta-estradiol (E2) are given. |
| format | Text |
| id | pubmed-524190 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2004 |
| publisher | BioMed Central |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-5241902004-10-24 Methods to find out the expression of activated genes Cekan, Sten Z Reprod Biol Endocrinol Review This review deals with the methods of identifying genes that have been activated by inner or outer impulses. The activation and subsequent expression of a gene can be detected by its transcription into a corresponding messenger ribonucleic acid (mRNA). Principles of the methods for identification of individual activated genes, as well as groups of activated genes are described, the former methods being mostly based on subtractive hybridization and serial analysis of gene expression (SAGE), the latter on microarrays. Examples of gene activation by the hormone 17beta-estradiol (E2) are given. BioMed Central 2004-09-23 /pmc/articles/PMC524190/ /pubmed/15385048 http://dx.doi.org/10.1186/1477-7827-2-68 Text en Copyright © 2004 Cekan; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an open-access article distributed under the terms of the Creative Commons Attribution License ( (http://creativecommons.org/licenses/by/2.0) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
| spellingShingle | Review Cekan, Sten Z Methods to find out the expression of activated genes |
| title | Methods to find out the expression of activated genes |
| title_full | Methods to find out the expression of activated genes |
| title_fullStr | Methods to find out the expression of activated genes |
| title_full_unstemmed | Methods to find out the expression of activated genes |
| title_short | Methods to find out the expression of activated genes |
| title_sort | methods to find out the expression of activated genes |
| topic | Review |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC524190/ https://www.ncbi.nlm.nih.gov/pubmed/15385048 http://dx.doi.org/10.1186/1477-7827-2-68 |
| work_keys_str_mv | AT cekanstenz methodstofindouttheexpressionofactivatedgenes |