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iRegNet3D: three-dimensional integrated regulatory network for the genomic analysis of coding and non-coding disease mutations
The mechanistic details of most disease-causing mutations remain poorly explored within the context of regulatory networks. We present a high-resolution three-dimensional integrated regulatory network (iRegNet3D) in the form of a web tool, where we resolve the interfaces of all known transcription f...
Autores principales: | Liang, Siqi, Tippens, Nathaniel D., Zhou, Yaoda, Mort, Matthew, Stenson, Peter D., Cooper, David N., Yu, Haiyuan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5241969/ https://www.ncbi.nlm.nih.gov/pubmed/28100260 http://dx.doi.org/10.1186/s13059-016-1138-2 |
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