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Medium throughput bisulfite sequencing for accurate detection of 5-methylcytosine and 5-hydroxymethylcytosine
BACKGROUND: Epigenetic modifications of DNA, such as 5-methylcytosine and 5-hydroxymethycytosine, play important roles in development and disease. Here, we present a cost-effective and versatile methodology for the analysis of DNA methylation in targeted genomic regions, which comprises multiplexed,...
Autores principales: | Chen, Gary G., Gross, Jeffrey A., Lutz, Pierre-Eric, Vaillancourt, Kathryn, Maussion, Gilles, Bramoulle, Alexandre, Théroux, Jean-François, Gardini, Elena S., Ehlert, Ulrike, Bourret, Geneviève, Masurel, Aurélie, Lepage, Pierre, Mechawar, Naguib, Turecki, Gustavo, Ernst, Carl |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5242011/ https://www.ncbi.nlm.nih.gov/pubmed/28100169 http://dx.doi.org/10.1186/s12864-017-3489-9 |
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