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Pharmacological characterization of cebranopadol a novel analgesic acting as mixed nociceptin/orphanin FQ and opioid receptor agonist

The aim of the study was to investigate the in vitro and in vivo pharmacological profile of cebranopadol, a novel agonist for opioid and nociceptin/orphanin FQ (N/OFQ) receptors (NOP). In vitro cebranopadol was assayed in calcium mobilization studies in cells coexpressing NOP or opioid receptors and...

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Detalles Bibliográficos
Autores principales: Rizzi, Anna, Cerlesi, Maria Camilla, Ruzza, Chiara, Malfacini, Davide, Ferrari, Federica, Bianco, Sara, Costa, Tommaso, Guerrini, Remo, Trapella, Claudio, Calo', Girolamo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5242173/
https://www.ncbi.nlm.nih.gov/pubmed/28116100
http://dx.doi.org/10.1002/prp2.247

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