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Inhibition of SGLT2 alleviates diabetic nephropathy by suppressing high glucose‐induced oxidative stress in type 1 diabetic mice
It is unclear whether the improvement in diabetic nephropathy by sodium glucose cotransporter 2 (SGLT2) inhibitors is caused by a direct effect on SGLT2 or by the improvement in hyperglycemia. Here, we investigated the effect of dapagliflozin on early‐stage diabetic nephropathy using a mouse model o...
Autores principales: | Hatanaka, Takashi, Ogawa, Daisuke, Tachibana, Hiromi, Eguchi, Jun, Inoue, Tatsuyuki, Yamada, Hiroshi, Takei, Kohji, Makino, Hirofumi, Wada, Jun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5242174/ https://www.ncbi.nlm.nih.gov/pubmed/28116093 http://dx.doi.org/10.1002/prp2.239 |
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