Cargando…

Distinct inflammatory phenotypes of microglia and monocyte‐derived macrophages in Alzheimer's disease models: effects of aging and amyloid pathology

Alzheimer's disease (AD) is a neurodegenerative disease characterized by formation of amyloid‐β (Aβ) plaques, activated microglia, and neuronal cell death leading to progressive dementia. Recent data indicate that microglia and monocyte‐derived macrophages (MDM) are key players in the initiatio...

Descripción completa

Detalles Bibliográficos
Autores principales:	Martin, Elodie, Boucher, Céline, Fontaine, Bertrand, Delarasse, Cécile
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2016
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5242297/ https://www.ncbi.nlm.nih.gov/pubmed/27723233 http://dx.doi.org/10.1111/acel.12522

Ejemplares similares

Complex role of chemokine mediators in animal models of Alzheimer's Disease
por: Martin, Elodie, et al.
Publicado: (2018)

New role of P2X7 receptor in an Alzheimer’s disease mouse model
por: Martin, Elodie, et al.
Publicado: (2018)

Distinct amyloid-β and tau-associated microglia profiles in Alzheimer’s disease
por: Gerrits, Emma, et al.
Publicado: (2021)

Microglia and monocytes in inflammatory CNS disease: integrating phenotype and function
por: Spiteri, Alanna G., et al.
Publicado: (2021)

The dynamics of monocytes and microglia in Alzheimer’s disease
por: Thériault, Peter, et al.
Publicado: (2015)

Innate Immune Cells: Monocytes, Monocyte-Derived Macrophages and Microglia as Therapeutic Targets for Alzheimer’s Disease and Multiple Sclerosis
por: Fani Maleki, Adham, et al.
Publicado: (2019)

Microglia and monocyte-derived macrophages: functionally distinct populations that act in concert in CNS plasticity and repair
por: London, Anat, et al.
Publicado: (2013)

Structural and functional distinctions of co-resident microglia and monocyte-derived macrophages after retinal degeneration
por: Ronning, Kaitryn E., et al.
Publicado: (2022)

Functional Impairment of Microglia Coincides with Beta-Amyloid Deposition in Mice with Alzheimer-Like Pathology
por: Krabbe, Grietje, et al.
Publicado: (2013)

Novel Alzheimer risk genes determine the microglia response to amyloid‐β but not to TAU pathology
por: Sierksma, Annerieke, et al.
Publicado: (2020)

The localization of molecularly distinct microglia populations to Alzheimer's disease pathologies using QUIVER
por: Shahidehpour, Ryan K., et al.
Publicado: (2023)

Fate mapping reveals that microglia and recruited monocyte-derived macrophages are definitively distinguishable by phenotype in the retina
por: O’Koren, E. G., et al.
Publicado: (2016)

Multiple Sclerosis: Microglia, Monocytes, and Macrophage-Mediated Demyelination
por: Prineas, John W, et al.
Publicado: (2021)

Clinical impact of anti-inflammatory microglia and macrophage phenotypes at glioblastoma margins
por: Noorani, Imran, et al.
Publicado: (2023)

Distinct Phenotypes of Inflammation Associated Macrophages and Microglia in the Prefrontal Cortex Schizophrenia Compared to Controls
por: Zhu, Yunting, et al.
Publicado: (2022)

Amyloid-β, p-tau and reactive microglia are pathological correlates of MRI cortical atrophy in Alzheimer’s disease
por: Frigerio, Irene, et al.
Publicado: (2021)

Inflammatory monocytes and microglia play independent roles in inflammatory ictogenesis
por: Howe, Charles L., et al.
Publicado: (2022)

β-amyloid binds to microglia Dectin-1 to induce inflammatory response in the pathogenesis of Alzheimer's disease
por: Zhao, Xia, et al.
Publicado: (2023)

Distinct microglia alternative splicing in Alzheimer's disease
por: Lu, Yanjun, et al.
Publicado: (2022)

The Translational Potential of Microglia and Monocyte-Derived Macrophages in Ischemic Stroke
por: Wicks, Elizabeth E., et al.
Publicado: (2022)

The Functions and Phenotypes of Microglia in Alzheimer’s Disease
por: Fujikawa, Risako, et al.
Publicado: (2023)

Microglia phenotypes are associated with subregional patterns of concomitant tau, amyloid-β and α-synuclein pathologies in the hippocampus of patients with Alzheimer’s disease and dementia with Lewy bodies
por: Fixemer, Sonja, et al.
Publicado: (2022)

Established Beta Amyloid Pathology Is Unaffected by TREM2 Elevation in Reactive Microglia in an Alzheimer’s Disease Mouse Model
por: Yuan, Qiuju, et al.
Publicado: (2021)

Roles of Microglial and Monocyte Chemokines and Their Receptors in Regulating Alzheimer's Disease-Associated Amyloid-β and Tau Pathologies
por: Guedes, Joana R., et al.
Publicado: (2018)

Microglia in Alzheimer’s Disease in the Context of Tau Pathology
por: Perea, Juan Ramón, et al.
Publicado: (2020)

Contribution of “Genuine Microglia” to Alzheimer's Disease Pathology
por: Hashioka, Sadayuki, et al.
Publicado: (2022)

Molecular Mechanisms Modulating the Phenotype of Macrophages and Microglia
por: Amici, Stephanie A., et al.
Publicado: (2017)

Phenotypic and Functional Heterogeneity of Monocytes and Macrophages
por: Hellman, Lars
Publicado: (2023)

Microglia receptors and their implications in the response to amyloid β for Alzheimer’s disease pathogenesis
por: Doens, Deborah, et al.
Publicado: (2014)

APOE and TREM2 regulate amyloid responsive microglia in Alzheimer’s disease
por: Nguyen, Aivi T., et al.
Publicado: (2020)

Modulation of β-Amyloid Fibril Formation in Alzheimer’s Disease by Microglia and Infection
por: Brown, Madeleine R., et al.
Publicado: (2020)

Monocyte and macrophage differentiation: circulation inflammatory monocyte as biomarker for inflammatory diseases
por: Yang, Jiyeon, et al.
Publicado: (2014)

Emergence of distinct and heterogeneous strains of amyloid beta with advanced Alzheimer’s disease pathology in Down syndrome
por: Maxwell, Alison M., et al.
Publicado: (2021)

Functional and Phenotypic Diversity of Microglia: Implication for Microglia-Based Therapies for Alzheimer’s Disease
por: Xu, Yi-Jun, et al.
Publicado: (2022)

Distinct Features of Brain-Resident Macrophages: Microglia and Non-Parenchymal Brain Macrophages
por: Lee, Eunju, et al.
Publicado: (2021)

Microglia and Macrophages in the Pathological Central and Peripheral Nervous Systems
por: Abe, Naoki, et al.
Publicado: (2020)

Prevention of Alzheimer Pathology by Blocking Neuregulin Signaling on Microglia
por: Liu, Jianguo, et al.
Publicado: (2023)

Microglia and Monocytes/Macrophages Polarization Reveal Novel Therapeutic Mechanism against Stroke
por: Kanazawa, Masato, et al.
Publicado: (2017)

Clearance of cerebral Aβ in Alzheimer’s disease: reassessing the role of microglia and monocytes
por: Zuroff, Leah, et al.
Publicado: (2017)

Distinction of Microglia and Macrophages in Glioblastoma: Close Relatives, Different Tasks?
por: Brandenburg, Susan, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_5hgm5buv1aq43csl4aogfqhou3