Cargando…

Preparation, Characterization and Evaluation of Drug Release Properties of Simvastatin-loaded PLGA Microspheres

Microspheres formulated from poly (D, L-lactic-co-glycolide) (PLGA), a biodegradable polymer, have been extensively evaluated as a drug delivery system. In this study, the preparation, characterization and drug release properties of the PLGA microspheres were evaluated. Simvastatin (SIM)-loaded PLGA...

Descripción completa

Detalles Bibliográficos
Autores principales:	Masaeli, Reza, S. Jafarzadeh Kashi, Tahereh, Dinarvand, Rassoul, Tahriri, Mohammadreza, Rakhshan, Vahid, Esfandyari-Manesh, Mehdi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Shaheed Beheshti University of Medical Sciences 2016
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5242366/ https://www.ncbi.nlm.nih.gov/pubmed/28228818

Ejemplares similares

Improved drug loading and antibacterial activity of minocycline-loaded PLGA nanoparticles prepared by solid/oil/water ion pairing method
por: Kashi, Tahereh Sadat Jafarzadeh, et al.
Publicado: (2012)

Effects of incorporation of 2.5 and 5 wt% TiO(2) nanotubes on fracture toughness, flexural strength, and microhardness of denture base poly methyl methacrylate (PMMA)
por: Abdulrazzaq Naji, Sahar, et al.
Publicado: (2018)

Delivery of disulfiram into breast cancer cells using folate-receptor-targeted PLGA-PEG nanoparticles: in vitro and in vivo investigations
por: Fasehee, Hamidreza, et al.
Publicado: (2016)

Preparation and In-vitro Evaluation of Controlled Release PLGA Microparticles Containing Triptoreline
por: Mahboubian, Alireza, et al.
Publicado: (2010)

Improved anticancer delivery of paclitaxel by albumin surface modification of PLGA nanoparticles
por: Esfandyari-Manesh, Mehdi, et al.
Publicado: (2015)

Preparation and Safety Evaluation of Topical Simvastatin Loaded NLCs for Vitiligo
por: Yazdani Ashtiani, Sahar, et al.
Publicado: (2021)

Local delivery of controlled-release simvastatin/PLGA/HAp microspheres enhances bone repair
por: Tai, I-Chun, et al.
Publicado: (2013)

Insulin-loaded PLGA microspheres for glucose-responsive release
por: Wu, Jun-Zi, et al.
Publicado: (2017)

Preparation and Antibacterial Activity Evaluation of 18-β-glycyrrhetinic Acid Loaded PLGA Nanoparticles
por: Darvishi, Behrad, et al.
Publicado: (2015)

Preparation and evaluation of amphipathic lipopeptide‐loaded PLGA microspheres as sustained‐release system for AIDS prevention
por: Jin, Huijuan, et al.
Publicado: (2020)

Preparation of PLGA Nanoparticles by Milling Spongelike PLGA Microspheres
por: Lee, Jimin, et al.
Publicado: (2022)

Preparation and Release Profiles in Vitro/Vivo of Galantamine Pamoate Loaded Poly (Lactideco-Glycolide) (PLGA) Microspheres
por: Du, Liping, et al.
Publicado: (2021)

Release of PLGA–encapsulated dexamethasone from microsphere loaded porous surfaces
por: Dawes, G. J. S., et al.
Publicado: (2009)

Protein Loading into Spongelike PLGA Microspheres
por: Kim, Yuyoung, et al.
Publicado: (2021)

Preparation, Characterization, In Vitro Release and Degradation of Cathelicidin-BF-30-PLGA Microspheres
por: Li, Lili, et al.
Publicado: (2014)

Drug-nanoencapsulated PLGA microspheres prepared by emulsion electrospray with controlled release behavior
por: Yao, Shenglian, et al.
Publicado: (2016)

Preparation and in vivo/in vitro characterization of Ticagrelor PLGA sustained-release microspheres for injection
por: Hao, Linkun, et al.
Publicado: (2021)

The effects of dentin bonding agent formulas on their polymerization quality, and together with tooth tissues on their microleakage and shear bond strength: an explorative 3-step experiment
por: Erfan, Mohmmad, et al.
Publicado: (2014)

Intra-articular injection PLGA blends sustained-release microspheres loaded with meloxicam: preparation, optimization, evaluation in vitro and in vivo
por: Sun, Zheng, et al.
Publicado: (2022)

The Effect of Polymer Blends on the In Vitro Release/Degradation and Pharmacokinetics of Moxidectin-Loaded PLGA Microspheres
por: Zhang, Hongjuan, et al.
Publicado: (2023)

Docetaxel Loaded PEG-PLGA Nanoparticles: Optimized Drug Loading, In-vitro Cytotoxicity and In-vivo Antitumor Effect
por: Noori Koopaei, Mona, et al.
Publicado: (2014)

A Comparison of Hepatocyte Cytotoxic Mechanisms for Docetaxel and PLGA-Docetaxel Nanoparticls
por: Daraei, Bahram, et al.
Publicado: (2017)

Efficacy of diode laser irradiation during dental bleaching in preventing enamel damage caused by bleaching
por: Azarbayjani, Zahra, et al.
Publicado: (2018)

Heuristic modeling of macromolecule release from PLGA microspheres
por: Szlęk, Jakub, et al.
Publicado: (2013)

Effects of simvastatin-loaded PLGA microspheres on treatment of rats with intervertebral disk degeneration and on 6-K-PGF1α and HIF-1α
por: Zhu, Kai, et al.
Publicado: (2020)

Effect of Stabilizers on Encapsulation Efficiency and Release Behavior of Exenatide-Loaded PLGA Microsphere Prepared by the W/O/W Solvent Evaporation Method
por: Park, Heejun, et al.
Publicado: (2019)

PLGA sustained-release microspheres loaded with an insoluble small-molecule drug: microfluidic-based preparation, optimization, characterization, and evaluation in vitro and in vivo
por: Su, Yue, et al.
Publicado: (2022)

Preparation of uniform-sized GeXIVA[1,2]-loaded PLGA microspheres as long-effective release system with high encapsulation efficiency
por: Li, Lu, et al.
Publicado: (2022)

Kinetics of pulpal temperature rise during light curing of 6 bonding agents from different generations, using light emitting diode and quartz-tungsten-halogen units: An in-vitro simulation
por: Khaksaran, Najmeh Khatoon, et al.
Publicado: (2015)

Preparation and evaluation of sustained release loxoprofen loaded microspheres
por: Venkatesan, P., et al.
Publicado: (2011)

Immunogenicity of pulsatile-release PLGA microspheres for single-injection vaccination
por: Guarecuco, Rohiverth, et al.
Publicado: (2018)

PEGylated apoptotic protein-loaded PLGA microspheres for cancer therapy
por: Byeon, Hyeong Jun, et al.
Publicado: (2015)

Polymerization behavior and thermal characteristics of two new composites at five temperatures: refrigeration to preheating
por: Jafarzadeh-Kashi, Tahereh Sadat, et al.
Publicado: (2011)

Rifapentine-linezolid-loaded PLGA microspheres for interventional therapy of cavitary pulmonary tuberculosis: preparation and in vitro characterization
por: Huang, Jieyun, et al.
Publicado: (2017)

Thermostabilization of inactivated polio vaccine in PLGA-based microspheres for pulsatile release
por: Tzeng, Stephany Y., et al.
Publicado: (2016)

Novel preparation method for sustained-release PLGA microspheres using water-in-oil-in-hydrophilic-oil-in-water emulsion
por: Hong, Xiaoyun, et al.
Publicado: (2013)

Formulation and Characterization of Ciprofloxacin loaded PLGA Microspheres for Applications in Orthopedic Infections
por: MOCANU, ANDREEA-GABRIELA, et al.
Publicado: (2017)

Local retention efficacy of steroid-loaded PLGA microspheres in epidural injection
por: Jang, Sowon, et al.
Publicado: (2022)

Preparation, Characterization and in vitro/in vivo Evaluation of Lovastatin-Loaded PLGA Microspheres by Local Administration for Femoral Head Necrosis
por: Sun, Yang, et al.
Publicado: (2021)

Preparation of PLGA microspheres loaded with niclosamide via microfluidic technology and their inhibition of Caco-2 cell activity in vitro
por: Tai, Yulei, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_c4suc7kslftipm4n68fsdvmdtj