Cargando…

Overexpression of Rad51 Predicts Poor Prognosis in Colorectal Cancer: Our Experience with 54 Patients

BACKGROUND: Aberrant Rad51 expression is implicated in the progression of human malignancies. However, the role of Rad51 in colorectal cancer (CRC) remains undefined. This study aimed to establish a relationship between Rad51 and clinicopathologic features of CRC. METHODS: We retrospectively examine...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Yan, Wang, Wei-ya, Xiao, Jiang-hong, Xu, Feng, Liao, Dian-ying, Xie, Li, Wang, Jin, Luo, Feng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5242438/ https://www.ncbi.nlm.nih.gov/pubmed/28099437 http://dx.doi.org/10.1371/journal.pone.0167868

Ejemplares similares

Retraction: Overexpression of Rad51 Predicts Poor Prognosis in Colorectal Cancer: Our Experience with 54 Patients
Publicado: (2018)

Rad51 and Rad54 ATPase activities are both required to modulate Rad51-dsDNA filament dynamics
por: Li, Xuan, et al.
Publicado: (2007)

Rad54 and Rdh54 prevent Srs2-mediated disruption of Rad51 presynaptic filaments
por: Meir, Aviv, et al.
Publicado: (2022)

Overexpression of Rad51C splice variants in colorectal tumors
por: Kalvala, Arjun, et al.
Publicado: (2014)

Cooperation of RAD51 and RAD54 in regression of a model replication fork
por: Bugreev, Dmitry V., et al.
Publicado: (2011)

RAD54 is essential for RAD51-mediated repair of meiotic DSB in Arabidopsis
por: Hernandez Sanchez-Rebato, Miguel, et al.
Publicado: (2021)

RAD54 family translocases counter genotoxic effects of RAD51 in human tumor cells
por: Mason, Jennifer M., et al.
Publicado: (2015)

Rdh54/Tid1 inhibits Rad51-Rad54-mediated D-loop formation and limits D-loop length
por: Shah, Shanaya Shital, et al.
Publicado: (2020)

RAD51AP1 and RAD54L Can Underpin Two Distinct RAD51-Dependent Routes of DNA Damage Repair via Homologous Recombination
por: Selemenakis, Platon, et al.
Publicado: (2022)

Cellular Dynamics of Rad51 and Rad54 in Response to Postreplicative Stress and DNA Damage in HeLa Cells
por: Choi, Eui-Hwan, et al.
Publicado: (2017)

Rad51 and Rad54 promote noncrossover recombination between centromere repeats on the same chromatid to prevent isochromosome formation
por: Onaka, Atsushi T., et al.
Publicado: (2016)

In vitro role of Rad54 in Rad51-ssDNA filament-dependent homology search and synaptic complexes formation
por: Tavares, Eliana Moreira, et al.
Publicado: (2019)

Detection of loss of heterozygosity at RAD51, RAD52, RAD54 and BRCA1 and BRCA2 loci in breast cancer: pathological correlations
por: Gonzalez, R, et al.
Publicado: (1999)

The bromodomain containing protein BRD-9 orchestrates RAD51–RAD54 complex formation and regulates homologous recombination-mediated repair
por: Zhou, Qin, et al.
Publicado: (2020)

Overexpression of HMGA1 confers radioresistance by transactivating RAD51 in cholangiocarcinoma
por: Song, Jianping, et al.
Publicado: (2021)

Nap1 stimulates homologous recombination by RAD51 and RAD54 in higher-ordered chromatin containing histone H1
por: Machida, Shinichi, et al.
Publicado: (2014)

Roles of XRCC2, RAD51B and RAD51D in RAD51-Independent SSA Recombination
por: Serra, Heïdi, et al.
Publicado: (2013)

RAD54 controls access to the invading 3′-OH end after RAD51-mediated DNA strand invasion in homologous recombination in Saccharomyces cerevisiae
por: Li, Xuan, et al.
Publicado: (2009)

Opposing Roles for Two Molecular Forms of Replication Protein A in Rad51-Rad54-Mediated DNA Recombination in Plasmodium falciparum
por: Gopalakrishnan, Anusha M., et al.
Publicado: (2013)

Expression of EhRAD54, EhRAD51, and EhBLM proteins during DNA repair by homologous recombination in Entamoeba histolytica
por: del Socorro Charcas-Lopez, Ma., et al.
Publicado: (2014)

Identification of Nanog as a novel inhibitor of Rad51
por: Xin, Ying, et al.
Publicado: (2022)

Rdh54 stabilizes Rad51 at displacement loop intermediates to regulate genetic exchange between chromosomes
por: Keymakh, Margaret, et al.
Publicado: (2022)

RAD21 cohesin overexpression is a prognostic and predictive marker exacerbating poor prognosis in KRAS mutant colorectal carcinomas
por: Deb, S, et al.
Publicado: (2014)

Author Correction: The bromodomain containing protein BRD-9 orchestrates RAD51–RAD54 complex formation and regulates homologous recombination-mediated repair
por: Zhou, Qin, et al.
Publicado: (2022)

Structure and function of the RAD51B-RAD51C-RAD51D-XRCC2 tumour suppressor
por: Greenhough, Luke A., et al.
Publicado: (2023)

Clinicopathological and Prognostic Characteristics of RAD51 in Colorectal Cancer
por: Lee, Jae-Ho, et al.
Publicado: (2020)

Overexpression of RAD51B predicts a preferable prognosis for non-small cell lung cancer patients
por: Wu, Mengyin, et al.
Publicado: (2017)

Homologous Pairing Activities of Two Rice RAD51 Proteins, RAD51A1 and RAD51A2
por: Morozumi, Yuichi, et al.
Publicado: (2013)

Arabidopsis RAD51, RAD51C and XRCC3 proteins form a complex and facilitate RAD51 localization on chromosomes for meiotic recombination
por: Su, Hang, et al.
Publicado: (2017)

Overexpression of CXCR2 predicts poor prognosis in patients with colorectal cancer
por: Zhao, Jingkun, et al.
Publicado: (2017)

Overexpression of RAD51 Enables PCR-Based Gene Targeting in Lager Yeast
por: Bernardi, Beatrice, et al.
Publicado: (2019)

Rad51 paralogs Rad55-Rad57 balance the anti-recombinase Srs2 in Rad51 filament formation
por: Liu, Jie, et al.
Publicado: (2011)

RAD51 paralogs synergize with RAD51 to protect reversed forks from cellular nucleases
por: Guh, Chia-Lun, et al.
Publicado: (2023)

Contributions of the RAD51 N-terminal domain to BRCA2-RAD51 interaction
por: Subramanyam, Shyamal, et al.
Publicado: (2013)

RAD51AP1 mediates RAD51 activity through nucleosome interaction
por: Pires, Elena, et al.
Publicado: (2021)

Hot on RAD51C: structure and functions of RAD51C‐XRCC3
por: Szakal, Barnabas, et al.
Publicado: (2023)

Correction for Gopalakrishnan and Kumar, Opposing Roles for Two Molecular Forms of Replication Protein A in Rad51-Rad54-Mediated DNA Recombination in Plasmodium falciparum
por: Gopalakrishnan, Anusha M., et al.
Publicado: (2015)

Rad51C-ATXN7 fusion gene expression in colorectal tumors
por: Kalvala, Arjun, et al.
Publicado: (2016)

The Shu complex interacts with Rad51 through the Rad51 paralogues Rad55–Rad57 to mediate error-free recombination
por: Godin, Stephen, et al.
Publicado: (2013)

Rad51, friend or foe?
por: Tan-Wong, Sue Mei, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_i541mpiqpa76edgmuodatvaspl