Cargando…

CapOX as neoadjuvant chemotherapy for locally advanced operable colon cancer patients: a prospective single-arm phase II trial

OBJECTIVE: The aim of this prospective, single-arm phase II trial was to confirm the safety and efficacy of neoadjuvant chemotherapy (NAC) using oxaliplatin plus capecitabine (CapOX) for patients with operable locally advanced colon cancer (CC). METHODS: Patients with computed tomography-defined T4...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Fangqi, Yang, Li, Wu, Yuchen, Li, Cong, Zhao, Jiang, Keranmu, Adili, Zheng, Hongtu, Huang, Dan, Wang, Lei, Tong, Tong, Xu, Junyan, Zhu, Ji, Cai, Sanjun, Xu, Ye
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	AME Publishing Company 2016
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5242445/ https://www.ncbi.nlm.nih.gov/pubmed/28174487 http://dx.doi.org/10.21147/j.issn.1000-9604.2016.06.05

Ejemplares similares

Comparative study of single-center patients with thyroid metastases from colorectal cancer and previously reported cases in the literature
por: Keranmu, Adili, et al.
Publicado: (2017)

Temporary Diverting Stoma Improves Recovery of Anastomotic Leakage after Anterior Resection for Rectal Cancer
por: Wu, Yuchen, et al.
Publicado: (2017)

Phase II study of capecitabine plus oxaliplatin (CapOX) as adjuvant chemotherapy for locally advanced rectal cancer (CORONA II)
por: Hattori, Norifumi, et al.
Publicado: (2019)

CapeOX perioperative chemotherapy versus postoperative chemotherapy for locally advanced resectable colon cancer: protocol for a two-period randomised controlled phase III trial
por: Liu, Fangqi, et al.
Publicado: (2019)

Efficacy and Safety of Capecitabine and Oxaliplatin (CapOX) as an Adjuvant Therapy in Japanese for Stage II/III Colon Cancer in a Group at High Risk of Recurrence in Retrospective Study
por: Osawa, Hiroshi, et al.
Publicado: (2015)

Early response to upfront neoadjuvant chemotherapy (CAPOX) alone in low- and intermediate-risk rectal cancer: a single-arm phase II trial
por: Deng, Xiangbing, et al.
Publicado: (2021)

Short-course radiotherapy combined with CAPOX and Toripalimab for the total neoadjuvant therapy of locally advanced rectal cancer: a randomized, prospective, multicentre, double-arm, phase II trial (TORCH)
por: Wang, Yaqi, et al.
Publicado: (2022)

Rectovaginal fistula after low anterior resection in Chinese patients with colorectal cancer
por: Zheng, Hongtu, et al.
Publicado: (2017)

Hypoxia Induces Growth Differentiation Factor 15 to Promote the Metastasis of Colorectal Cancer via PERK-eIF2α Signaling
por: Zheng, Hongtu, et al.
Publicado: (2020)

Neutrophil-to-lymphocyte and platelet-to-lymphocyte ratios predict chemotherapy outcomes and prognosis in patients with colorectal cancer and synchronous liver metastasis
por: Wu, Yuchen, et al.
Publicado: (2016)

Adjuvant Chemotherapy after Neoadjuvant Chemotherapy and Long-term Outcomes of CAPOX Plus Bevacizumab Followed by TME for High-risk Localized Rectal Cancer
por: Nishimura, Junichi, et al.
Publicado: (2020)

Phase I Dose Escalation Study with Expansion Cohort of the Addition of Nab-Paclitaxel to Capecitabine and Oxaliplatin (CapOx) as First-Line Treatment of Metastatic Esophagogastric Adenocarcinoma (ACTION Study)
por: Schokker, Sandor, et al.
Publicado: (2019)

Neoadjuvant Chemotherapy With CAPOX Versus Chemoradiation for Locally Advanced Rectal Cancer With Uninvolved Mesorectal Fascia (CONVERT): Initial Results of a Phase III Trial
por: Mei, Wei-Jian, et al.
Publicado: (2023)

Laparoscopic surgery may decrease the risk of clinical anastomotic leakage and a nomogram to predict anastomotic leakage after anterior resection for rectal cancer
por: Zheng, Hongtu, et al.
Publicado: (2018)

Postoperative Adjuvant Chemotherapy Regimen of CAPOX Combined With Ninjin'yoeito in an Elderly Patient With Stage III Colon Cancer: A Case Report
por: Aomatsu, Naoki, et al.
Publicado: (2020)

A randomized two arm phase III study in patients post radical resection of liver metastases of colorectal cancer to investigate bevacizumab in combination with capecitabine plus oxaliplatin (CAPOX) vs CAPOX alone as adjuvant treatment
por: Snoeren, Nikol, et al.
Publicado: (2010)

Adding Three Cycles of CAPOX after Neoadjuvant Chemoradiotherapy Increases the Rates of Complete Response for Locally Advanced Rectal Cancer
por: Zhai, Zhiwei, et al.
Publicado: (2021)

Concomitant boost IMRT-based neoadjuvant chemoradiotherapy for clinical stage II/III rectal adenocarcinoma: results of a phase II study
por: Zhu, Ji, et al.
Publicado: (2014)

Prolonged Capecitabine Chemotherapy Following Capecitabine and Oxaliplatin (CAPOX) Regimen Chemotherapy Failed to Improve Survival of Stage III Colorectal Cancer After Radical Resection
por: Xu, Ju Ling, et al.
Publicado: (2019)

Retrospective comparison of efficacy and safety of CAPOX and FOLFOX regimens as adjuvant treatment in patients with stage III colon cancer
por: Degirmencioglu, Serkan, et al.
Publicado: (2019)

Adjuvant chemotherapy in stage II–III operated colon cancer patients from a nontrial cohort in a low colon cancer prevalence country with predominant use of modified CAPOX
por: Ramaswamy, Anant, et al.
Publicado: (2019)

Neoadjuvant Chemotherapy for Colon Cancer
por: Roth, Marc T., et al.
Publicado: (2020)

Phase II trial of first-line chemoradiotherapy with intensity-modulated radiation therapy followed by chemotherapy for synchronous unresectable distant metastases rectal adenocarcinoma
por: Zhu, Ji, et al.
Publicado: (2013)

Is there a prognostic value of tumor location among Chinese patients with colorectal cancer?
por: Liu, Fangqi, et al.
Publicado: (2017)

Recognition of Anterior Peritoneal Reflections and Their Relationship With Rectal Tumors Using Rectal Magnetic Resonance Imaging
por: Yiqun, Sun, et al.
Publicado: (2016)

Pathological Features and Survival Outcomes of Young Patients with Operable Colon Cancer: Are They Homogeneous?
por: Li, Qingguo, et al.
Publicado: (2014)

Comment on “Neoadjuvant Chemotherapy With CAPOX Versus Chemoradiation for Locally Advanced Rectal Cancer With Uninvolved Mesorectal Fascia (CONVERT): Initial Results of a Phase III Trial” by Mei et al.: Two Overtreatments Compared
por: Mroczkowski, Paweł
Publicado: (2023)

Specific microRNAs as novel biomarkers for combination chemotherapy resistance detection of colon adenocarcinoma
por: Hu, Jinsong, et al.
Publicado: (2015)

Risk scoring system for recurrence after simultaneous resection of colorectal cancer liver metastasis
por: Wu, Yuchen, et al.
Publicado: (2021)

Neoadjuvant Pembrolizumab and Chemotherapy in Resectable Esophageal Cancer: An Open-Label, Single-Arm Study (PEN-ICE)
por: Duan, Hongtao, et al.
Publicado: (2022)

The Role of Neoadjuvant Chemotherapy in Locally Advanced Colon Cancer
por: Body, Amy, et al.
Publicado: (2021)

Extramural depth of rectal cancer tumor invasion at thin-section MRI: predicting treatment response to neoadjuvant chemoradiation
por: Tong, Tong, et al.
Publicado: (2015)

Higher FOXP3-TSDR demethylation rates in adjacent normal tissues in patients with colon cancer were associated with worse survival
por: Zhuo, Changhua, et al.
Publicado: (2014)

A feasibility randomised controlled trial of short-term fasting prior to CAPOX chemotherapy for stage 2/3 colorectal cancer: SWiFT protocol
por: Shingler, Ellie, et al.
Publicado: (2019)

Clinical factors related to severe enterocolitis after adjuvant CAPOX for colorectal cancer: a retrospective analysis
por: Felismino, Tiago Cordeiro, et al.
Publicado: (2020)

Ovarian metastases from ileum cancer in a patient with germline EPCAM gene deletion successfully treated with surgical resection and CAPOX chemotherapy: a case report
por: Iwata, Narushi, et al.
Publicado: (2020)

The efficiency of neoadjuvant chemotherapy in colon cancer with mismatch repair deficiency
por: Yunlong, Wu, et al.
Publicado: (2022)

Photoacoustic Computed Tomography of Breast Cancer in Response to Neoadjuvant Chemotherapy
por: Lin, Li, et al.
Publicado: (2021)

A multicenter single-arm trial of sintilimab in combination with chemotherapy for neoadjuvant treatment of resectable esophageal cancer (SIN-ICE study)
por: Duan, Hongtao, et al.
Publicado: (2021)

Neoadjuvant Chemotherapy in Asian Patients With Locally Advanced Gastric Cancer
por: Tong, Xie, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_0u0p0po7o0up6gkk77qah1ntin