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Acute and Chronic Sustained Hypoxia Do Not Substantially Regulate Amyloid-β Peptide Generation In Vivo

BACKGROUND: Recent epidemiological evidence has linked hypoxia with the development of Alzheimer disease (AD). A number of in vitro and in vivo studies have reported that hypoxia can induce amyloid-β peptide accumulation through various molecular mechanisms including the up-regulation of the amyloid...

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Detalles Bibliográficos
Autores principales: Serrano-Pozo, Alberto, Sánchez-García, Manuel A., Heras-Garvín, Antonio, March-Díaz, Rosana, Navarro, Victoria, Vizuete, Marisa, López-Barneo, José, Vitorica, Javier, Pascual, Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5242476/
https://www.ncbi.nlm.nih.gov/pubmed/28099462
http://dx.doi.org/10.1371/journal.pone.0170345