Cargando…

ArrayD: A general purpose software for Microarray design

BACKGROUND: Microarray is a high-throughput technology to study expression of thousands of genes in parallel. A critical aspect of microarray production is the design aimed at space optimization while maximizing the number of gene probes and their replicates to be spotted. RESULTS: We have developed...

Descripción completa

Detalles Bibliográficos
Autores principales: Sharma, Anu, Srivastava, Gyan Prakash, Sharma, Vineet K, Ramachandran, Srinivasan
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC524372/
https://www.ncbi.nlm.nih.gov/pubmed/15461789
http://dx.doi.org/10.1186/1471-2105-5-142
_version_ 1782121898235133952
author Sharma, Anu
Srivastava, Gyan Prakash
Sharma, Vineet K
Ramachandran, Srinivasan
author_facet Sharma, Anu
Srivastava, Gyan Prakash
Sharma, Vineet K
Ramachandran, Srinivasan
author_sort Sharma, Anu
collection PubMed
description BACKGROUND: Microarray is a high-throughput technology to study expression of thousands of genes in parallel. A critical aspect of microarray production is the design aimed at space optimization while maximizing the number of gene probes and their replicates to be spotted. RESULTS: We have developed a software called 'ArrayD' that offers various alternative design solutions for an array given a set of user requirements. The user feeds the following inputs: type of source plates to be used, number of gene probes to be printed, number of replicates and number of pins to be used for printing. The solutions are stored in a text file. The choice of a design solution to be used will be governed by the spotting chemistry to be used and the accuracy of the robot. CONCLUSIONS: ArrayD is a software for standard cartesian robots. The software aids users in preparing a judicious and elegant design. ArrayD is universally applicable and is available at .
format Text
id pubmed-524372
institution National Center for Biotechnology Information
language English
publishDate 2004
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-5243722004-10-29 ArrayD: A general purpose software for Microarray design Sharma, Anu Srivastava, Gyan Prakash Sharma, Vineet K Ramachandran, Srinivasan BMC Bioinformatics Software BACKGROUND: Microarray is a high-throughput technology to study expression of thousands of genes in parallel. A critical aspect of microarray production is the design aimed at space optimization while maximizing the number of gene probes and their replicates to be spotted. RESULTS: We have developed a software called 'ArrayD' that offers various alternative design solutions for an array given a set of user requirements. The user feeds the following inputs: type of source plates to be used, number of gene probes to be printed, number of replicates and number of pins to be used for printing. The solutions are stored in a text file. The choice of a design solution to be used will be governed by the spotting chemistry to be used and the accuracy of the robot. CONCLUSIONS: ArrayD is a software for standard cartesian robots. The software aids users in preparing a judicious and elegant design. ArrayD is universally applicable and is available at . BioMed Central 2004-10-02 /pmc/articles/PMC524372/ /pubmed/15461789 http://dx.doi.org/10.1186/1471-2105-5-142 Text en Copyright © 2004 Sharma et al; licensee BioMed Central Ltd.
spellingShingle Software
Sharma, Anu
Srivastava, Gyan Prakash
Sharma, Vineet K
Ramachandran, Srinivasan
ArrayD: A general purpose software for Microarray design
title ArrayD: A general purpose software for Microarray design
title_full ArrayD: A general purpose software for Microarray design
title_fullStr ArrayD: A general purpose software for Microarray design
title_full_unstemmed ArrayD: A general purpose software for Microarray design
title_short ArrayD: A general purpose software for Microarray design
title_sort arrayd: a general purpose software for microarray design
topic Software
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC524372/
https://www.ncbi.nlm.nih.gov/pubmed/15461789
http://dx.doi.org/10.1186/1471-2105-5-142
work_keys_str_mv AT sharmaanu arraydageneralpurposesoftwareformicroarraydesign
AT srivastavagyanprakash arraydageneralpurposesoftwareformicroarraydesign
AT sharmavineetk arraydageneralpurposesoftwareformicroarraydesign
AT ramachandransrinivasan arraydageneralpurposesoftwareformicroarraydesign