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MICA Expression Is Regulated by Cell Adhesion and Contact in a FAK/Src-Dependent Manner
MICA is a major ligand for the NKG2D immune receptor, which plays a key role in activating natural killer (NK) cells and cytotoxic T cells. We analyzed NKG2D ligand expression on a range of cell types and could demonstrate that MICA expression levels were closely linked to cellular growth mode. Whil...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5243850/ https://www.ncbi.nlm.nih.gov/pubmed/28154561 http://dx.doi.org/10.3389/fimmu.2016.00687 |