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MICA Expression Is Regulated by Cell Adhesion and Contact in a FAK/Src-Dependent Manner

MICA is a major ligand for the NKG2D immune receptor, which plays a key role in activating natural killer (NK) cells and cytotoxic T cells. We analyzed NKG2D ligand expression on a range of cell types and could demonstrate that MICA expression levels were closely linked to cellular growth mode. Whil...

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Detalles Bibliográficos
Autores principales: Moncayo, Gerald, Lin, Da, McCarthy, Michael T., Watson, Aleksandra A., O’Callaghan, Christopher A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5243850/
https://www.ncbi.nlm.nih.gov/pubmed/28154561
http://dx.doi.org/10.3389/fimmu.2016.00687