PLIN2 is a Key Regulator of the Unfolded Protein Response and Endoplasmic Reticulum Stress Resolution in Pancreatic β Cells

Progressive pancreatic β cell failure underlies the transition of impaired glucose tolerance to overt diabetes; endoplasmic reticulum (ER) stress expedites β cell failure in this situation. ER stress can be elicited by lipotoxicity and an increased demand for insulin in diabetes. We previously repor...

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Detalles Bibliográficos
Autores principales: Chen, Elaine, Tsai, Tsung Huang, Li, Lan, Saha, Pradip, Chan, Lawrence, Chang, Benny Hung-Junn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5244387/
https://www.ncbi.nlm.nih.gov/pubmed/28102311
http://dx.doi.org/10.1038/srep40855

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