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Elevated collagen-I augments tumor progressive signals, intravasation and metastasis of prolactin-induced estrogen receptor alpha positive mammary tumor cells

BACKGROUND: The development and progression of estrogen receptor alpha positive (ERα+) breast cancer has been linked epidemiologically to prolactin. However, activation of the canonical mediator of prolactin, STAT5, is associated with more differentiated cancers and better prognoses. We have reporte...

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Detalles Bibliográficos
Autores principales: Barcus, Craig E., O’Leary, Kathleen A., Brockman, Jennifer L., Rugowski, Debra E., Liu, Yuming, Garcia, Nancy, Yu, Menggang, Keely, Patricia J., Eliceiri, Kevin W., Schuler, Linda A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5244528/
https://www.ncbi.nlm.nih.gov/pubmed/28103936
http://dx.doi.org/10.1186/s13058-017-0801-1

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