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GDE2 is essential for neuronal survival in the postnatal mammalian spinal cord

BACKGROUND: Glycerophosphodiester phosphodiesterase 2 (GDE2) is a six-transmembrane protein that cleaves glycosylphosphatidylinositol (GPI) anchors to regulate GPI-anchored protein activity at the cell surface. In the developing spinal cord, GDE2 utilizes its enzymatic function to regulate the produ...

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Detalles Bibliográficos
Autores principales:	Cave, Clinton, Park, Sungjin, Rodriguez, Marianeli, Nakamura, Mai, Hoke, Ahmet, Pletnikov, Mikhail, Sockanathan, Shanthini
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5244531/ https://www.ncbi.nlm.nih.gov/pubmed/28103900 http://dx.doi.org/10.1186/s13024-017-0148-1

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