A preliminary study on the potential of Mycoplasma pneumoniae to induce dyskaryotic change in respiratory epithelium in adult community-acquired pneumonia

BACKGROUND: This study aimed to explore the cellular morphology of respiratory epithelium in Mycoplasma pneumonia (MpP) patients. MATERIALS AND METHODS: The cast-off cell morphological findings from bronchoscopic brushings in MpP and community-acquired pneumonia (CAP) caused by typical pathogens wer...

Descripción completa

Detalles Bibliográficos
Autores principales: An, Shu-Chang, Yang, Dong-Hong, Luo, Chao-Feng, Chen, Xin, Liu, Guo-Tian, Weng, Yan, Liu, Jing-Zhe, Shang, Ying, Wang, Rui-Qin, Gao, Zhan-Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2016
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5244644/
https://www.ncbi.nlm.nih.gov/pubmed/28163727
http://dx.doi.org/10.4103/1735-1995.192497
_version_ 1782496730399375360
author An, Shu-Chang
Yang, Dong-Hong
Luo, Chao-Feng
Chen, Xin
Liu, Guo-Tian
Weng, Yan
Liu, Jing-Zhe
Shang, Ying
Wang, Rui-Qin
Gao, Zhan-Cheng
author_facet An, Shu-Chang
Yang, Dong-Hong
Luo, Chao-Feng
Chen, Xin
Liu, Guo-Tian
Weng, Yan
Liu, Jing-Zhe
Shang, Ying
Wang, Rui-Qin
Gao, Zhan-Cheng
author_sort An, Shu-Chang
collection PubMed
description BACKGROUND: This study aimed to explore the cellular morphology of respiratory epithelium in Mycoplasma pneumonia (MpP) patients. MATERIALS AND METHODS: The cast-off cell morphological findings from bronchoscopic brushings in MpP and community-acquired pneumonia (CAP) caused by typical pathogens were reviewed. RESULTS: Compared with the CAP group, cellular dysplasia in respiratory tract epithelial brushings was significantly greater in MpP patients (P = 0.033). CONCLUSION: Unique biological characteristics and mechanisms of pathogenesis of Mycoplasma pneumoniae (Mp) may result in dyskaryotic changes in respiratory epithelium in adult MpP.
format Online
Article
Text
id pubmed-5244644
institution National Center for Biotechnology Information
language English
publishDate 2016
publisher Medknow Publications & Media Pvt Ltd
record_format MEDLINE/PubMed
spelling pubmed-52446442017-02-03 A preliminary study on the potential of Mycoplasma pneumoniae to induce dyskaryotic change in respiratory epithelium in adult community-acquired pneumonia An, Shu-Chang Yang, Dong-Hong Luo, Chao-Feng Chen, Xin Liu, Guo-Tian Weng, Yan Liu, Jing-Zhe Shang, Ying Wang, Rui-Qin Gao, Zhan-Cheng J Res Med Sci Short Communication BACKGROUND: This study aimed to explore the cellular morphology of respiratory epithelium in Mycoplasma pneumonia (MpP) patients. MATERIALS AND METHODS: The cast-off cell morphological findings from bronchoscopic brushings in MpP and community-acquired pneumonia (CAP) caused by typical pathogens were reviewed. RESULTS: Compared with the CAP group, cellular dysplasia in respiratory tract epithelial brushings was significantly greater in MpP patients (P = 0.033). CONCLUSION: Unique biological characteristics and mechanisms of pathogenesis of Mycoplasma pneumoniae (Mp) may result in dyskaryotic changes in respiratory epithelium in adult MpP. Medknow Publications & Media Pvt Ltd 2016-10-18 /pmc/articles/PMC5244644/ /pubmed/28163727 http://dx.doi.org/10.4103/1735-1995.192497 Text en Copyright: © 2016 Journal of Research in Medical Sciences http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Short Communication
An, Shu-Chang
Yang, Dong-Hong
Luo, Chao-Feng
Chen, Xin
Liu, Guo-Tian
Weng, Yan
Liu, Jing-Zhe
Shang, Ying
Wang, Rui-Qin
Gao, Zhan-Cheng
A preliminary study on the potential of Mycoplasma pneumoniae to induce dyskaryotic change in respiratory epithelium in adult community-acquired pneumonia
title A preliminary study on the potential of Mycoplasma pneumoniae to induce dyskaryotic change in respiratory epithelium in adult community-acquired pneumonia
title_full A preliminary study on the potential of Mycoplasma pneumoniae to induce dyskaryotic change in respiratory epithelium in adult community-acquired pneumonia
title_fullStr A preliminary study on the potential of Mycoplasma pneumoniae to induce dyskaryotic change in respiratory epithelium in adult community-acquired pneumonia
title_full_unstemmed A preliminary study on the potential of Mycoplasma pneumoniae to induce dyskaryotic change in respiratory epithelium in adult community-acquired pneumonia
title_short A preliminary study on the potential of Mycoplasma pneumoniae to induce dyskaryotic change in respiratory epithelium in adult community-acquired pneumonia
title_sort preliminary study on the potential of mycoplasma pneumoniae to induce dyskaryotic change in respiratory epithelium in adult community-acquired pneumonia
topic Short Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5244644/
https://www.ncbi.nlm.nih.gov/pubmed/28163727
http://dx.doi.org/10.4103/1735-1995.192497
work_keys_str_mv AT anshuchang apreliminarystudyonthepotentialofmycoplasmapneumoniaetoinducedyskaryoticchangeinrespiratoryepitheliuminadultcommunityacquiredpneumonia
AT yangdonghong apreliminarystudyonthepotentialofmycoplasmapneumoniaetoinducedyskaryoticchangeinrespiratoryepitheliuminadultcommunityacquiredpneumonia
AT luochaofeng apreliminarystudyonthepotentialofmycoplasmapneumoniaetoinducedyskaryoticchangeinrespiratoryepitheliuminadultcommunityacquiredpneumonia
AT chenxin apreliminarystudyonthepotentialofmycoplasmapneumoniaetoinducedyskaryoticchangeinrespiratoryepitheliuminadultcommunityacquiredpneumonia
AT liuguotian apreliminarystudyonthepotentialofmycoplasmapneumoniaetoinducedyskaryoticchangeinrespiratoryepitheliuminadultcommunityacquiredpneumonia
AT wengyan apreliminarystudyonthepotentialofmycoplasmapneumoniaetoinducedyskaryoticchangeinrespiratoryepitheliuminadultcommunityacquiredpneumonia
AT liujingzhe apreliminarystudyonthepotentialofmycoplasmapneumoniaetoinducedyskaryoticchangeinrespiratoryepitheliuminadultcommunityacquiredpneumonia
AT shangying apreliminarystudyonthepotentialofmycoplasmapneumoniaetoinducedyskaryoticchangeinrespiratoryepitheliuminadultcommunityacquiredpneumonia
AT wangruiqin apreliminarystudyonthepotentialofmycoplasmapneumoniaetoinducedyskaryoticchangeinrespiratoryepitheliuminadultcommunityacquiredpneumonia
AT gaozhancheng apreliminarystudyonthepotentialofmycoplasmapneumoniaetoinducedyskaryoticchangeinrespiratoryepitheliuminadultcommunityacquiredpneumonia
AT anshuchang preliminarystudyonthepotentialofmycoplasmapneumoniaetoinducedyskaryoticchangeinrespiratoryepitheliuminadultcommunityacquiredpneumonia
AT yangdonghong preliminarystudyonthepotentialofmycoplasmapneumoniaetoinducedyskaryoticchangeinrespiratoryepitheliuminadultcommunityacquiredpneumonia
AT luochaofeng preliminarystudyonthepotentialofmycoplasmapneumoniaetoinducedyskaryoticchangeinrespiratoryepitheliuminadultcommunityacquiredpneumonia
AT chenxin preliminarystudyonthepotentialofmycoplasmapneumoniaetoinducedyskaryoticchangeinrespiratoryepitheliuminadultcommunityacquiredpneumonia
AT liuguotian preliminarystudyonthepotentialofmycoplasmapneumoniaetoinducedyskaryoticchangeinrespiratoryepitheliuminadultcommunityacquiredpneumonia
AT wengyan preliminarystudyonthepotentialofmycoplasmapneumoniaetoinducedyskaryoticchangeinrespiratoryepitheliuminadultcommunityacquiredpneumonia
AT liujingzhe preliminarystudyonthepotentialofmycoplasmapneumoniaetoinducedyskaryoticchangeinrespiratoryepitheliuminadultcommunityacquiredpneumonia
AT shangying preliminarystudyonthepotentialofmycoplasmapneumoniaetoinducedyskaryoticchangeinrespiratoryepitheliuminadultcommunityacquiredpneumonia
AT wangruiqin preliminarystudyonthepotentialofmycoplasmapneumoniaetoinducedyskaryoticchangeinrespiratoryepitheliuminadultcommunityacquiredpneumonia
AT gaozhancheng preliminarystudyonthepotentialofmycoplasmapneumoniaetoinducedyskaryoticchangeinrespiratoryepitheliuminadultcommunityacquiredpneumonia

Ejemplares similares