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Survival of mature T cells in the periphery is intrinsically dependent on GIMAP1 in mice

An effective immune system depends upon the survival of mature T cells in the periphery. Members of the GIMAP family of GTPases have been proposed to regulate this homeostasis, supported by the paucity of peripheral T cells in rodents deficient for either GIMAP1 or GIMAP5. It is unclear whether this...

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Detalles Bibliográficos
Autores principales:	Datta, Preeta, Webb, Louise M.C., Avdo, Inxhina, Pascall, John, Butcher, Geoffrey W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2016
Materias:	Molecular immunology and signaling
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5244661/ https://www.ncbi.nlm.nih.gov/pubmed/27792288 http://dx.doi.org/10.1002/eji.201646599

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