Cargando…

Translating translation into patient benefit for atopic eczema

This review considers, in the context of British Skin Foundation (BSF)‐funded translational research into atopic eczema conducted in Newcastle, the complex interactions between clinical and non‐clinical scientists in both academia and industry and how this may have impacted on clinical care. However...

Descripción completa

Detalles Bibliográficos
Autores principales: Reynolds, N.J., Sinha, A., Elias, M.S., Meggitt, S.J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5244670/
https://www.ncbi.nlm.nih.gov/pubmed/27667309
http://dx.doi.org/10.1111/bjd.14909
_version_ 1782496735433588736
author Reynolds, N.J.
Sinha, A.
Elias, M.S.
Meggitt, S.J.
author_facet Reynolds, N.J.
Sinha, A.
Elias, M.S.
Meggitt, S.J.
author_sort Reynolds, N.J.
collection PubMed
description This review considers, in the context of British Skin Foundation (BSF)‐funded translational research into atopic eczema conducted in Newcastle, the complex interactions between clinical and non‐clinical scientists in both academia and industry and how this may have impacted on clinical care. However, research in individual centres does not occur in isolation and clinically relevant outcomes from collaborative research are increasingly supported through regional and national networks. This is illustrated by our trial of azathioprine in adults with atopic eczema conducted across centres in the North East of England that employed pharmacogenetic dosimetry. Correspondingly the formation of a UK Translational Network for Translational Research in Dermatology (UK TREND) has facilitated the development of a UK‐wide network to support atopic eczema projects based on an e‐Delphi prioritisation exercise.
format Online
Article
Text
id pubmed-5244670
institution National Center for Biotechnology Information
language English
publishDate 2016
publisher John Wiley and Sons Inc.
record_format MEDLINE/PubMed
spelling pubmed-52446702017-01-25 Translating translation into patient benefit for atopic eczema Reynolds, N.J. Sinha, A. Elias, M.S. Meggitt, S.J. Br J Dermatol British Skin Foundation, Skin Deep ‐ 20 Years of Research, 20th Anniversary Conference, 13th October 2016, Royal College of Physicians, London, U.K. Publication of this supplement was supported by Stiefel, a GSK company This review considers, in the context of British Skin Foundation (BSF)‐funded translational research into atopic eczema conducted in Newcastle, the complex interactions between clinical and non‐clinical scientists in both academia and industry and how this may have impacted on clinical care. However, research in individual centres does not occur in isolation and clinically relevant outcomes from collaborative research are increasingly supported through regional and national networks. This is illustrated by our trial of azathioprine in adults with atopic eczema conducted across centres in the North East of England that employed pharmacogenetic dosimetry. Correspondingly the formation of a UK Translational Network for Translational Research in Dermatology (UK TREND) has facilitated the development of a UK‐wide network to support atopic eczema projects based on an e‐Delphi prioritisation exercise. John Wiley and Sons Inc. 2016-09-26 2016-10 /pmc/articles/PMC5244670/ /pubmed/27667309 http://dx.doi.org/10.1111/bjd.14909 Text en © 2016 The Authors. British Journal of Dermatology published by John Wiley & Sons Ltd on behalf of British Association of Dermatologists. This is an open access article under the terms of the Creative Commons Attribution (http://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle British Skin Foundation, Skin Deep ‐ 20 Years of Research, 20th Anniversary Conference, 13th October 2016, Royal College of Physicians, London, U.K. Publication of this supplement was supported by Stiefel, a GSK company
Reynolds, N.J.
Sinha, A.
Elias, M.S.
Meggitt, S.J.
Translating translation into patient benefit for atopic eczema
title Translating translation into patient benefit for atopic eczema
title_full Translating translation into patient benefit for atopic eczema
title_fullStr Translating translation into patient benefit for atopic eczema
title_full_unstemmed Translating translation into patient benefit for atopic eczema
title_short Translating translation into patient benefit for atopic eczema
title_sort translating translation into patient benefit for atopic eczema
topic British Skin Foundation, Skin Deep ‐ 20 Years of Research, 20th Anniversary Conference, 13th October 2016, Royal College of Physicians, London, U.K. Publication of this supplement was supported by Stiefel, a GSK company
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5244670/
https://www.ncbi.nlm.nih.gov/pubmed/27667309
http://dx.doi.org/10.1111/bjd.14909
work_keys_str_mv AT reynoldsnj translatingtranslationintopatientbenefitforatopiceczema
AT sinhaa translatingtranslationintopatientbenefitforatopiceczema
AT eliasms translatingtranslationintopatientbenefitforatopiceczema
AT meggittsj translatingtranslationintopatientbenefitforatopiceczema