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HLA–DRB1 Amino Acid Positions 11/13, 71, and 74 Are Associated With Inflammation Level, Disease Activity, and the Health Assessment Questionnaire Score in Patients With Inflammatory Polyarthritis

OBJECTIVE: Rheumatoid arthritis (RA) susceptibility HLA–DRB1 haplotypes based on amino acid positions 11/13, 71, and 74 predict radiographic damage. The mechanism of action is unknown, but it may be mediated by inflammation. We undertook this study to systematically investigate the effect of these a...

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Detalles Bibliográficos
Autores principales:	Ling, Stephanie F., Viatte, Sebastien, Lunt, Mark, Van Sijl, Alper M., Silva‐Fernandez, Lucia, Symmons, Deborah P. M., Young, Adam, Macgregor, Alexander J., Barton, Anne
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2016
Materias:	Rheumatoid Arthritis
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5244675/ https://www.ncbi.nlm.nih.gov/pubmed/27274008 http://dx.doi.org/10.1002/art.39780

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