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Vaccine candidates derived from a novel infectious cDNA clone of an American genotype dengue virus type 2
BACKGROUND: A dengue virus type 2 (DEN-2 Tonga/74) isolated from a 1974 epidemic was characterized by mild illness and belongs to the American genotype of DEN-2 viruses. To prepare a vaccine candidate, a previously described 30 nucleotide deletion (Δ30) in the 3' untranslated region of DEN-4 ha...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2004
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC524489/ https://www.ncbi.nlm.nih.gov/pubmed/15461822 http://dx.doi.org/10.1186/1471-2334-4-39 |