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Crystal structures of the transpeptidase domain of the Mycobacterium tuberculosis penicillin‐binding protein PonA1 reveal potential mechanisms of antibiotic resistance

Mycobacterium tuberculosis is a human respiratory pathogen that causes the deadly disease tuberculosis. The rapid global spread of antibiotic‐resistant M. tuberculosis makes tuberculosis infections difficult to treat. To overcome this problem new effective antimicrobial strategies are urgently neede...

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Detalles Bibliográficos
Autores principales:	Filippova, Ekaterina V., Kieser, Karen J., Luan, Chi‐Hao, Wawrzak, Zdzislaw, Kiryukhina, Olga, Rubin, Eric J., Anderson, Wayne F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2016
Materias:	Editor's Choice
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5245116/ https://www.ncbi.nlm.nih.gov/pubmed/27101811 http://dx.doi.org/10.1111/febs.13738

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