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Multiple linear combination (MLC) regression tests for common variants adapted to linkage disequilibrium structure
By jointly analyzing multiple variants within a gene, instead of one at a time, gene‐based multiple regression can improve power, robustness, and interpretation in genetic association analysis. We investigate multiple linear combination (MLC) test statistics for analysis of common variants under rea...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5245123/ https://www.ncbi.nlm.nih.gov/pubmed/27885705 http://dx.doi.org/10.1002/gepi.22024 |