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Significance of clearing differentiated thyroid carcinoma lymph node by high-frequency color Doppler ultrasonography

We compared the clinical effects and prognosis of patients receiving lymph node dissection after surgical removal of the thyroid tissues and those not receiving it after the removal. A total of 80 patients diagnosed with differentiated thyroid carcinoma (DTC) by our hospital from March 2012 to March...

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Autores principales: Liu, Bing, Qin, Huadong, Zhang, Bin, Shi, Tiefeng, Li, Chuanle, Liu, Yao, Song, Meiyue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5245155/
https://www.ncbi.nlm.nih.gov/pubmed/28123550
http://dx.doi.org/10.3892/ol.2016.5450
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author Liu, Bing
Qin, Huadong
Zhang, Bin
Shi, Tiefeng
Li, Chuanle
Liu, Yao
Song, Meiyue
author_facet Liu, Bing
Qin, Huadong
Zhang, Bin
Shi, Tiefeng
Li, Chuanle
Liu, Yao
Song, Meiyue
author_sort Liu, Bing
collection PubMed
description We compared the clinical effects and prognosis of patients receiving lymph node dissection after surgical removal of the thyroid tissues and those not receiving it after the removal. A total of 80 patients diagnosed with differentiated thyroid carcinoma (DTC) by our hospital from March 2012 to March 2014 were successively included in the study. The cases were divided into the control group (n=36 cases) and observation group (n=44 cases), and the two groups underwent total or subtotal resection of the thyroid. In the control group, patients underwent preoperative high-frequency color ultrasonography, and the most suspicious lymph node was removed. In the observation group, patients underwent preoperative high-frequency color ultrasonography, and the surgeons cleared the lymph node of the widest range. Difference in clinical effects and prognosis of the two groups were compared. After nearly a year's follow-up observation, the tumor recurrence rate of the observation group was significantly lower than that of the control group and the survival rate of the observation group was significantly higher than that of the control group (P<0.05). The rate of surgery complications and comparative difference of the two patient groups had no statistical significance (P>0.05). When comparing the data of lymphatic metastasis tested by preoperative high-frequency color ultrasonography with intraoperative diagnosed figures, sensitivity was 97.4%, specificity 33.3%, positive predictive value 90.2% and the negative predictive value 66.7%. In conclusion, removal of the lymph node for DTC patients having undergone thyroid tissue excision with preoperative high-frequency color ultrasonography can be beneficial to improve the effects along with reduction in the recurrence rate.
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spelling pubmed-52451552017-01-25 Significance of clearing differentiated thyroid carcinoma lymph node by high-frequency color Doppler ultrasonography Liu, Bing Qin, Huadong Zhang, Bin Shi, Tiefeng Li, Chuanle Liu, Yao Song, Meiyue Oncol Lett Articles We compared the clinical effects and prognosis of patients receiving lymph node dissection after surgical removal of the thyroid tissues and those not receiving it after the removal. A total of 80 patients diagnosed with differentiated thyroid carcinoma (DTC) by our hospital from March 2012 to March 2014 were successively included in the study. The cases were divided into the control group (n=36 cases) and observation group (n=44 cases), and the two groups underwent total or subtotal resection of the thyroid. In the control group, patients underwent preoperative high-frequency color ultrasonography, and the most suspicious lymph node was removed. In the observation group, patients underwent preoperative high-frequency color ultrasonography, and the surgeons cleared the lymph node of the widest range. Difference in clinical effects and prognosis of the two groups were compared. After nearly a year's follow-up observation, the tumor recurrence rate of the observation group was significantly lower than that of the control group and the survival rate of the observation group was significantly higher than that of the control group (P<0.05). The rate of surgery complications and comparative difference of the two patient groups had no statistical significance (P>0.05). When comparing the data of lymphatic metastasis tested by preoperative high-frequency color ultrasonography with intraoperative diagnosed figures, sensitivity was 97.4%, specificity 33.3%, positive predictive value 90.2% and the negative predictive value 66.7%. In conclusion, removal of the lymph node for DTC patients having undergone thyroid tissue excision with preoperative high-frequency color ultrasonography can be beneficial to improve the effects along with reduction in the recurrence rate. D.A. Spandidos 2017-01 2016-11-30 /pmc/articles/PMC5245155/ /pubmed/28123550 http://dx.doi.org/10.3892/ol.2016.5450 Text en Copyright: © Liu et al. This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License (https://creativecommons.org/licenses/by-nc-nd/4.0/) , which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.
spellingShingle Articles
Liu, Bing
Qin, Huadong
Zhang, Bin
Shi, Tiefeng
Li, Chuanle
Liu, Yao
Song, Meiyue
Significance of clearing differentiated thyroid carcinoma lymph node by high-frequency color Doppler ultrasonography
title Significance of clearing differentiated thyroid carcinoma lymph node by high-frequency color Doppler ultrasonography
title_full Significance of clearing differentiated thyroid carcinoma lymph node by high-frequency color Doppler ultrasonography
title_fullStr Significance of clearing differentiated thyroid carcinoma lymph node by high-frequency color Doppler ultrasonography
title_full_unstemmed Significance of clearing differentiated thyroid carcinoma lymph node by high-frequency color Doppler ultrasonography
title_short Significance of clearing differentiated thyroid carcinoma lymph node by high-frequency color Doppler ultrasonography
title_sort significance of clearing differentiated thyroid carcinoma lymph node by high-frequency color doppler ultrasonography
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5245155/
https://www.ncbi.nlm.nih.gov/pubmed/28123550
http://dx.doi.org/10.3892/ol.2016.5450
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