Expression of a Mutant SEMA3A Protein with Diminished Signalling Capacity Does Not Alter ALS-Related Motor Decline, or Confer Changes in NMJ Plasticity after BotoxA-Induced Paralysis of Male Gastrocnemic Muscle

Terminal Schwann cells (TSCs) are specialized cells that envelop the motor nerve terminal, and play a role in the maintenance and regeneration of neuromuscular junctions (NMJs). The chemorepulsive protein semaphorin 3A (SEMA3A) is selectively up-regulated in TSCs on fast-fatigable muscle fibers foll...

Descripción completa

Detalles Bibliográficos
Autores principales: Moloney, Elizabeth B., Hobo, Barbara, De Winter, Fred, Verhaagen, Joost
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5245795/
https://www.ncbi.nlm.nih.gov/pubmed/28103314
http://dx.doi.org/10.1371/journal.pone.0170314

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5245795/
https://www.ncbi.nlm.nih.gov/pubmed/28103314
http://dx.doi.org/10.1371/journal.pone.0170314

Ejemplares similares