Protection Elicited by Nasal Immunization with Recombinant Pneumococcal Surface Protein A (rPspA) Adjuvanted with Whole-Cell Pertussis Vaccine (wP) against Co-Colonization of Mice with Streptococcus pneumoniae

A promising alternative vaccine candidate to reduce the burden of pneumococcal diseases is the protein antigen PspA (Pneumococcal surface protein A). Since concomitant colonization with two or more pneumococcal strains is very common in children, we aimed to determine if immunization with PspA would...

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Detalles Bibliográficos
Autores principales: Tostes, Rafaella O., Rodrigues, Tasson C., da Silva, Josefa B., Schanoski, Alessandra S., Oliveira, Maria Leonor S., Miyaji, Eliane N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5245875/
https://www.ncbi.nlm.nih.gov/pubmed/28103277
http://dx.doi.org/10.1371/journal.pone.0170157

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