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CDK-regulated dimerization of M18BP1 on a Mis18 hexamer is necessary for CENP-A loading
Centromeres are unique chromosomal loci that promote the assembly of kinetochores, macromolecular complexes that bind spindle microtubules during mitosis. In most organisms, centromeres lack defined genetic features. Rather, they are specified epigenetically by a centromere-specific histone H3 varia...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
eLife Sciences Publications, Ltd
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5245964/ https://www.ncbi.nlm.nih.gov/pubmed/28059702 http://dx.doi.org/10.7554/eLife.23352 |