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Activation of the JAK-STAT Signaling Pathway after In Vitro Stimulation with IFNß in Multiple Sclerosis Patients According to the Therapeutic Response to IFNß
Interferon beta (IFNß) is a common treatment used for multiple sclerosis (MS) which acts through the activation of the JAK-STAT pathway. However, this therapy is not always effective and currently there are no reliable biomarkers to predict therapeutic response. We postulate that the heterogeneity i...
Autores principales: | Hurtado-Guerrero, Isaac, Pinto-Medel, Maria Jesús, Urbaneja, Patricia, Rodriguez- Bada, Jose Luis, León, Antonio, Guerrero, Miguel, Fernández, Óscar, Leyva, Laura, Oliver-Martos, Begoña |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5245989/ https://www.ncbi.nlm.nih.gov/pubmed/28103257 http://dx.doi.org/10.1371/journal.pone.0170031 |
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