Cargando…

A human microprotein that interacts with the mRNA decapping complex

Proteomic detection of non-annotated microproteins indicates the translation of hundreds of small open reading frames in human cells, but whether these microproteins are functional is unknown. Here, we report the discovery and characterization of a 7-kilodalton human microprotein we named non-annota...

Descripción completa

Detalles Bibliográficos
Autores principales:	D’Lima, Nadia G., Ma, Jiao, Winkler, Lauren, Chu, Qian, Loh, Ken H., Corpuz, Elizabeth O., Budnik, Bogdan A., Lykke-Andersen, Jens, Saghatelian, Alan, Slavoff, Sarah A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5247292/ https://www.ncbi.nlm.nih.gov/pubmed/27918561 http://dx.doi.org/10.1038/nchembio.2249

Ejemplares similares

The influence of transcript assembly on the proteogenomics discovery of microproteins
por: Ma, Jiao, et al.
Publicado: (2018)

Identification of Microprotein–Protein Interactions via APEX Tagging
por: Chu, Qian, et al.
Publicado: (2017)

Unannotated microprotein EMBOW regulates the interactome and chromatin and mitotic functions of WDR5
por: Chen, Yanran, et al.
Publicado: (2023)

Regulation of the ER stress response by a mitochondrial microprotein
por: Chu, Qian, et al.
Publicado: (2019)

Discovery of Human sORF-Encoded Polypeptides (SEPs) in Cell Lines and Tissue
por: Ma, Jiao, et al.
Publicado: (2014)

Comparative Membrane Proteomics Reveals a Nonannotated E. coli Heat Shock Protein
por: Yuan, Peijia, et al.
Publicado: (2017)

Control of mRNA decapping by autoinhibition
por: Paquette, David R, et al.
Publicado: (2018)

Eukaryotic mRNA Decapping Activation
por: Vidya, Elva, et al.
Publicado: (2022)

Nudt3 is an mRNA decapping enzyme that modulates cell migration
por: Grudzien-Nogalska, Ewa, et al.
Publicado: (2016)

Peptidomic discovery of short open reading frame-encoded peptides in human cells
por: Slavoff, Sarah A., et al.
Publicado: (2012)

A unique mRNA decapping complex in trypanosomes
por: Kramer, Susanne, et al.
Publicado: (2023)

The TINCR ubiquitin-like microprotein is a tumor suppressor in squamous cell carcinoma
por: Morgado-Palacin, Lucia, et al.
Publicado: (2023)

Microproteins: Overlooked regulators of physiology and disease
por: Hassel, Keira R., et al.
Publicado: (2023)

Targeting Poxvirus Decapping Enzymes and mRNA Decay to Generate an Effective Oncolytic Virus
por: Burgess, Hannah M., et al.
Publicado: (2018)

Biomolecular condensates amplify mRNA decapping by biasing enzyme conformation
por: Tibble, Ryan W., et al.
Publicado: (2021)

microProtein Prediction Program (miP3): A Software for Predicting microProteins and Their Target Transcription Factors
por: de Klein, Niek, et al.
Publicado: (2015)

Microproteins (miPs) – the next big thing
por: Feller, Stephan
Publicado: (2012)

Membrane-association of mRNA decapping factors is independent of stress in budding yeast
por: Huch, Susanne, et al.
Publicado: (2016)

The microprotein Minion controls cell fusion and muscle formation
por: Zhang, Qiao, et al.
Publicado: (2017)

Molecular basis of the selective processing of short mRNA substrates by the DcpS mRNA decapping enzyme
por: Fuchs, Anna-Lisa, et al.
Publicado: (2020)

Microproteins in skeletal muscle: hidden keys in muscle physiology
por: Bonilauri, Bernardo, et al.
Publicado: (2021)

De novo birth of functional microproteins in the human lineage
por: Vakirlis, Nikolaos, et al.
Publicado: (2022)

3′ uridylation precedes decapping in a novel pathway of bulk mRNA turnover
por: Rissland, Olivia S., et al.
Publicado: (2009)

The C-terminal α–α superhelix of Pat is required for mRNA decapping in metazoa
por: Braun, Joerg E, et al.
Publicado: (2010)

Dcp2: an mRNA decapping enzyme that adopts many different shapes and forms
por: Wurm, Jan Philip, et al.
Publicado: (2019)

mRNA decapping is an evolutionarily conserved modulator of neuroendocrine signaling that controls development and ageing
por: Borbolis, Fivos, et al.
Publicado: (2020)

Is mRNA decapping by ApaH like phosphatases present in eukaryotes beyond the Kinetoplastida?
por: Castañeda Londoño, Paula Andrea, et al.
Publicado: (2021)

Vaccinia virus D10 has broad decapping activity that is regulated by mRNA splicing
por: Ly, Michael, et al.
Publicado: (2022)

In Vitro Reconstitution of a Cellular Phase-Transition Process that Involves the mRNA Decapping Machinery**
por: Fromm, Simon A, et al.
Publicado: (2014)

Structure and function of the bacterial decapping enzyme NudC
por: Höfer, Katharina, et al.
Publicado: (2016)

Identification of functional domains in Arabidopsis thaliana mRNA decapping enzyme (AtDcp2)
por: Gunawardana, Dilantha, et al.
Publicado: (2008)

The deadenylase components Not2p, Not3p, and Not5p promote mRNA decapping
por: Alhusaini, Najwa, et al.
Publicado: (2016)

2'-O-methylation of the mRNA cap protects RNAs from decapping and degradation by DXO
por: Picard-Jean, Frédéric, et al.
Publicado: (2018)

mRNA Decapping and 5′-3′ Decay Contribute to the Regulation of ABA Signaling in Arabidopsis thaliana
por: Wawer, Izabela, et al.
Publicado: (2018)

Mutations in genes encoding regulators of mRNA decapping and translation initiation: links to intellectual disability
por: Weil, Dominique, et al.
Publicado: (2020)

An mRNA decapping mutant deficient in P body assembly limits mRNA stabilization in response to osmotic stress
por: Huch, Susanne, et al.
Publicado: (2017)

Decapping factor Dcp2 controls mRNA abundance and translation to adjust metabolism and filamentation to nutrient availability
por: Vijjamarri, Anil Kumar, et al.
Publicado: (2023)

Approaches to identify and characterize microProteins and their potential uses in biotechnology
por: Bhati, Kaushal Kumar, et al.
Publicado: (2018)

Plant microProteins: Small but powerful modulators of plant development
por: Kushwaha, Amit Kumar, et al.
Publicado: (2022)

The RNA-binding protein Y14 inhibits mRNA decapping and modulates processing body formation
por: Chuang, Tzu-Wei, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_71o27itlnevorn91g3jrkebrhu