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A fluorescent probe for cysteine depalmitoylation reveals dynamic APT signaling
Hundreds of human proteins are modified by reversible palmitoylation of cysteine residues (S-palmitoylation), but the regulation of depalmitoylation is poorly understood. Here, we develop “depalmitoylation probes” (DPPs), small molecule fluorophores to monitor the endogenous activity levels of “eras...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5247352/ https://www.ncbi.nlm.nih.gov/pubmed/27992880 http://dx.doi.org/10.1038/nchembio.2262 |