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Transcriptional Regulation by ATOH1 and its Target SPDEF in the Intestine

BACKGROUND & AIMS: The transcription factor atonal homolog 1 (ATOH1) controls the fate of intestinal progenitors downstream of the Notch signaling pathway. Intestinal progenitors that escape Notch activation express high levels of ATOH1 and commit to a secretory lineage fate, implicating ATOH1 a...

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Detalles Bibliográficos
Autores principales: Lo, Yuan-Hung, Chung, Eunah, Li, Zhaohui, Wan, Ying-Wooi, Mahe, Maxime M., Chen, Min-Shan, Noah, Taeko K., Bell, Kristin N., Yalamanchili, Hari Krishna, Klisch, Tiemo J., Liu, Zhandong, Park, Joo-Seop, Shroyer, Noah F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5247424/
https://www.ncbi.nlm.nih.gov/pubmed/28174757
http://dx.doi.org/10.1016/j.jcmgh.2016.10.001