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Transcriptional Regulation by ATOH1 and its Target SPDEF in the Intestine
BACKGROUND & AIMS: The transcription factor atonal homolog 1 (ATOH1) controls the fate of intestinal progenitors downstream of the Notch signaling pathway. Intestinal progenitors that escape Notch activation express high levels of ATOH1 and commit to a secretory lineage fate, implicating ATOH1 a...
Autores principales: | Lo, Yuan-Hung, Chung, Eunah, Li, Zhaohui, Wan, Ying-Wooi, Mahe, Maxime M., Chen, Min-Shan, Noah, Taeko K., Bell, Kristin N., Yalamanchili, Hari Krishna, Klisch, Tiemo J., Liu, Zhandong, Park, Joo-Seop, Shroyer, Noah F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5247424/ https://www.ncbi.nlm.nih.gov/pubmed/28174757 http://dx.doi.org/10.1016/j.jcmgh.2016.10.001 |
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