Pharmacokinetics, Biotransformation, and Excretion of [(14)C]Etelcalcetide (AMG 416) Following a Single Microtracer Intravenous Dose in Patients with Chronic Kidney Disease on Hemodialysis

Etelcalcetide (AMG 416) is a novel synthetic peptide calcium-sensing receptor activator in clinical development as an intravenous calcimimetic for the treatment of secondary hyperparathyroidism in patients with chronic kidney disease (CKD) on hemodialysis. Etelcalcetide is composed of seven d-aminoa...

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Detalles Bibliográficos
Autores principales: Subramanian, Raju, Zhu, Xiaochun, Hock, M. Benjamin, Sloey, Bethlyn J., Wu, Benjamin, Wilson, Sarah F., Egbuna, Ogo, Slatter, J. Greg, Xiao, Jim, Skiles, Gary L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2016
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5247555/
https://www.ncbi.nlm.nih.gov/pubmed/27517676
http://dx.doi.org/10.1007/s40262-016-0433-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5247555/
https://www.ncbi.nlm.nih.gov/pubmed/27517676
http://dx.doi.org/10.1007/s40262-016-0433-0

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