Isolated Ileal Stricture Secondary to Antigen-Negative GI Histoplasmosis in a Patient on Immunosuppressive Therapy

We present a case of antigen-negative disseminated histoplasmosis manifesting as an isolated ileal stricture in a patient on chronic infliximab and methotrexate. Diagnosis can be challenging due to imperfect tests, and this condition should remain in the differential, even with negative testing. Mor...

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Autores principales: Rowe, Kyle M., Green, Michael, Nehme, Fredy, Tofteland, Nathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American College of Gastroenterology 2017
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5247624/
https://www.ncbi.nlm.nih.gov/pubmed/28144615
http://dx.doi.org/10.14309/crj.2017.10
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author Rowe, Kyle M.
Green, Michael
Nehme, Fredy
Tofteland, Nathan
author_facet Rowe, Kyle M.
Green, Michael
Nehme, Fredy
Tofteland, Nathan
author_sort Rowe, Kyle M.
collection PubMed
description We present a case of antigen-negative disseminated histoplasmosis manifesting as an isolated ileal stricture in a patient on chronic infliximab and methotrexate. Diagnosis can be challenging due to imperfect tests, and this condition should remain in the differential, even with negative testing. Mortality of untreated disseminated histoplasmosis can be as high as 80%.
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spelling pubmed-52476242017-01-31 Isolated Ileal Stricture Secondary to Antigen-Negative GI Histoplasmosis in a Patient on Immunosuppressive Therapy Rowe, Kyle M. Green, Michael Nehme, Fredy Tofteland, Nathan ACG Case Rep J Case Report We present a case of antigen-negative disseminated histoplasmosis manifesting as an isolated ileal stricture in a patient on chronic infliximab and methotrexate. Diagnosis can be challenging due to imperfect tests, and this condition should remain in the differential, even with negative testing. Mortality of untreated disseminated histoplasmosis can be as high as 80%. American College of Gastroenterology 2017-01-18 /pmc/articles/PMC5247624/ /pubmed/28144615 http://dx.doi.org/10.14309/crj.2017.10 Text en Copyright © Rowe et al. This is an open-access article. This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/4.0/
spellingShingle Case Report
Rowe, Kyle M.
Green, Michael
Nehme, Fredy
Tofteland, Nathan
Isolated Ileal Stricture Secondary to Antigen-Negative GI Histoplasmosis in a Patient on Immunosuppressive Therapy
title Isolated Ileal Stricture Secondary to Antigen-Negative GI Histoplasmosis in a Patient on Immunosuppressive Therapy
title_full Isolated Ileal Stricture Secondary to Antigen-Negative GI Histoplasmosis in a Patient on Immunosuppressive Therapy
title_fullStr Isolated Ileal Stricture Secondary to Antigen-Negative GI Histoplasmosis in a Patient on Immunosuppressive Therapy
title_full_unstemmed Isolated Ileal Stricture Secondary to Antigen-Negative GI Histoplasmosis in a Patient on Immunosuppressive Therapy
title_short Isolated Ileal Stricture Secondary to Antigen-Negative GI Histoplasmosis in a Patient on Immunosuppressive Therapy
title_sort isolated ileal stricture secondary to antigen-negative gi histoplasmosis in a patient on immunosuppressive therapy
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5247624/
https://www.ncbi.nlm.nih.gov/pubmed/28144615
http://dx.doi.org/10.14309/crj.2017.10
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AT toftelandnathan isolatedilealstricturesecondarytoantigennegativegihistoplasmosisinapatientonimmunosuppressivetherapy

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