The New Synthetic H(2)S-Releasing SDSS Protects MC3T3-E1 Osteoblasts against H(2)O(2)-Induced Apoptosis by Suppressing Oxidative Stress, Inhibiting MAPKs, and Activating the PI3K/Akt Pathway

Reactive oxygen species (ROS) are important in osteoporosis development. Oxidative stress induces apoptosis of osteoblasts and arrest of their differentiation. Both Danshensu (DSS) and hydrogen sulfide (H(2)S) produce significant antioxidant effect in various systems. In this study, we synthesized S...

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Detalles Bibliográficos
Autores principales: Yan, Xiaofei, Wu, Haixia, Wu, Zhiyuan, Hua, Fei, Liang, Dong, Sun, Hong, Yang, Yong, Huang, Dejian, Bian, Jin-Song
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5247634/
https://www.ncbi.nlm.nih.gov/pubmed/28163684
http://dx.doi.org/10.3389/fphar.2017.00007

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