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A conserved TLR5 binding and activation hot spot on flagellin

Flagellin is a bacterial protein that polymerizes into the flagellar filament and is essential for bacterial motility. When flagellated bacteria invade the host, flagellin is recognized by Toll-like receptor 5 (TLR5) as a pathogen invasion signal and eventually evokes the innate immune response. Her...

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Detalles Bibliográficos
Autores principales: Song, Wan Seok, Jeon, Ye Ji, Namgung, Byeol, Hong, Minsun, Yoon, Sung-il
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5247705/
https://www.ncbi.nlm.nih.gov/pubmed/28106112
http://dx.doi.org/10.1038/srep40878

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