Tanshinone IIA induces intrinsic apoptosis in osteosarcoma cells both in vivo and in vitro associated with mitochondrial dysfunction

Tanshinone IIA (Tan IIA), a phytochemical derived from the roots of Salvia miltiorrhiza, has been shown to inhibit growth and induce apoptosis in various cancer cells. The association of its inhibitory effect on the primary malignant bone tumor, osteosarcoma, with mitochondrial dysfunction remains u...

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Detalles Bibliográficos
Autores principales: Huang, Sheng-Teng, Huang, Chao-Chun, Huang, Wen-Liang, Lin, Tsu-Kung, Liao, Pei-Lin, Wang, Pei-Wen, Liou, Chia-Wei, Chuang, Jiin-Haur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5247764/
https://www.ncbi.nlm.nih.gov/pubmed/28106052
http://dx.doi.org/10.1038/srep40382

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